894767-26-1 Usage
General Description
(R)-4-oxopiperidine-2-carboxylic acid, also known as L-pipecolic acid, is a naturally occurring cyclic amino acid. It is a key intermediate in the biosynthesis of the non-protein amino acid, L-lysine, and is involved in the metabolism of the neurotransmitter, GABA. L-pipecolic acid has been found to have potential neuroprotective and anti-inflammatory properties, and has been studied for its potential therapeutic applications in treating neurodegenerative diseases and inflammatory conditions. It is also used as a precursor in the synthesis of pharmaceuticals and agrochemicals, making it a valuable chemical compound with diverse applications in research and industry.
Check Digit Verification of cas no
The CAS Registry Mumber 894767-26-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,4,7,6 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 894767-26:
(8*8)+(7*9)+(6*4)+(5*7)+(4*6)+(3*7)+(2*2)+(1*6)=241
241 % 10 = 1
So 894767-26-1 is a valid CAS Registry Number.
894767-26-1Relevant articles and documents
A new synthesis of (2S)-4-oxopipecolic acid by thermal rearrangement of enantiopure spirocyclopropaneisoxazolidine
Machetti, Fabrizio,Cordero, Franca M.,De Sarlo, Francesco,Guarna, Antonio,Brandi, Alberto
, p. 4205 - 4208 (2007/10/03)
A novel synthesis of (2S)-4-oxo-pipecolic acid is reported. The synthetic route employs as a key step the diastereoselective cycloaddition of the N- glycosylnitrone 7 to methylenecyclopropane followed by thermal rearrangement of the spirocyclopropaneisoxazolidine 8a. Stereoselective reduction of the N- BOC methyl ester of 4-oxopipecolic acid by L-selectride gives the protected cis-4-hydroxy-pipecolic acid 14.
