895135-99-6

Basic information

• Product Name: C₂₁H₁₇N₃O
• Synonyms: C₂₁H₁₇N₃O
• CAS NO: 895135-99-6
• Molecular Weight: 327.385
• Mol File: 895135-99-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₇N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₇N₃O(895135-99-6)
• EPA Substance Registry System: C₂₁H₁₇N₃O(895135-99-6)

Safety Data

• Hazardous Substances Data: 895135-99-6(Hazardous Substances Data)

Upstream product

• 76-84-6 triphenylmethyl alcohol 
• 930-33-6 2,4-dihydro-1,2,4-triazol-3-one 

Relevant articles and documents

TRIAZOLONE, TETRAZOLONE AND IMIDAZOLONE DERIVATIVES FOR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS

The present invention concerns substituted triazolone, tetrazolone and imidazolone derivatives according to the general Formula (I) a pharmaceutically acceptable acid or base addition salt thereof, a stereochemically isomeric form thereof, an N-oxide form thereof or a quaternary ammonium salt thereof, wherein the variables are defined in Claim 1, having selective α2C-adrenoceptor antagonist activity. It further relates to their preparation, compositions comprising them and their use as a medicine. The compounds according to the invention are usefull for the prevention and/or treatment of central nervous system disorders, mood disorders, anxi- ety disorders, stress-related disorders associated with depression and/or anxiety, cognitive disorders, personality disorders, schizoaffective disorders, Parkinson's disease, dementia of the Alzheimer's type, chronic pain conditions, neurodegenerative diseases, addiction disorders, mood disorders and sexual dysfunction.