895155-78-9 Usage
Description
XLR12 is a trifluorobutyl analog of XLR11, which is a 5-fluoropentyl analog of UR-144. Both XLR11 and UR-144 are synthetic cannabinoids that have been detected in herbal blends. However, the physiological and toxicological properties of XLR12 are currently unknown.
Used in Forensic Applications:
XLR12 is used as a forensic tool for the detection and analysis of synthetic cannabinoids in various samples. Its unique chemical structure allows for accurate identification and differentiation from other substances.
Used in Research Applications:
XLR12 serves as a research compound for studying the effects and mechanisms of synthetic cannabinoids. This helps scientists and researchers to better understand their impact on the human body and develop potential treatments or interventions if necessary.
Used in Pharmaceutical Development:
Although its physiological and toxicological properties are not yet known, XLR12 may be used in the development of new pharmaceuticals targeting the cannabinoid receptors. Further research is required to explore its potential therapeutic applications.
Used in Toxicological Studies:
XLR12 can be utilized in toxicological studies to evaluate the safety and potential risks associated with synthetic cannabinoids. This information is crucial for understanding the consequences of their use and informing regulatory decisions.
Check Digit Verification of cas no
The CAS Registry Mumber 895155-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,5,1,5 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 895155-78:
(8*8)+(7*9)+(6*5)+(5*1)+(4*5)+(3*5)+(2*7)+(1*8)=219
219 % 10 = 9
So 895155-78-9 is a valid CAS Registry Number.
895155-78-9Relevant articles and documents
Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity
Frost, Jennifer M.,Dart, Michael J.,Tietje, Karin R.,Garrison, Tiffany R.,Grayson, George K.,Daza, Anthony V.,El-Kouhen, Odile F.,Yao, Betty B.,Hsieh, Gin C.,Pai, Madhavi,Zhu, Chang Z.,Chandran, Prasant,Meyer, Michael D.
, p. 295 - 315 (2010/06/11)
Several 3-acylindoles with high affinity for the CB2 cannabinoid receptor and selectivity over the CB1 receptor have been prepared. A variety of 3-acyl substituents were investigated, and the tetramethylcyclopropyl group was found to lead to high affinity CB2 agonists (5, 16). Substitution at the N1-indole position was then examined. A series of aminoalkylindoles was prepared and several substituted aminoethyl derivatives were active (23-27, 5) at the CB2 receptor.Astudy of N1 nonaromatic side chain variants provided potent agonists at the CB2 receptor (16, 35-41, 44-47, 49-54, and 57-58). Several polar side chains (alcohols, oxazolidinone) were well-tolerated for CB2 receptor activity (41, 50), while others (amide, acid) led to weaker or inactive compounds (55 and 56). N1 aromatic side chains also afforded several high affinity CB2 receptor agonists (61, 63, 65, and 69) but were generally less potent in an in vitro CB2 functional assay than were nonaromatic side chain analogues.
