89525-51-9

Basic information

• Product Name: 2-BROMO-4,5-DIMETHOXYBENZYLAMINE
• Synonyms: 2-BROMO-4,5-DIMETHOXYBENZYLAMINE;1-(2-Bromo-4,5-dimethoxyphenyl)methanamine;(2-bromo-4,5-dimethoxyphenyl)methanamine
• CAS NO: 89525-51-9
• Molecular Formula: C₉H₁₂BrNO₂
• Molecular Weight: 246.1
• Mol File: 89525-51-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BROMO-4,5-DIMETHOXYBENZYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4,5-DIMETHOXYBENZYLAMINE(89525-51-9)
• EPA Substance Registry System: 2-BROMO-4,5-DIMETHOXYBENZYLAMINE(89525-51-9)

Safety Data

• Hazardous Substances Data: 89525-51-9(Hazardous Substances Data)

Upstream product

• 198204-67-0 2-bromo-4,5-dimethoxybenzaldehyde oxime 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 54370-00-2 2-bromo-4,5-dimethoxybenzyl alcohol 
• 53207-00-4 1-bromo-2-(bromomethyl)-4,5-dimethoxybenzene 

Downstream Products

• 124617-62-5 (2-Bromo-4,5-dimethoxy-benzyl)-but-(Z)-ylidene-amine 
• 89525-45-1 [1-(2-Bromo-4,5-dimethoxy-phenyl)-meth-(E)-ylidene]-phenyl-amine 
• 129764-14-3 N-(2-bromo-4,5-dimethoxybenzyl)aniline 
• 401503-94-4 N-(2-bromo-4,5-dimethoxybenzyl)-N-phenyl tert-butyl acetate 
• 24285-10-7 6,7-dimethoxy-3-phenylisoquinoline 
• 124617-63-6 N-(2-Bromo-4,5-dimethoxy-benzyl)-thioacetimidic acid methyl ester 
• 89506-12-7 [(C₆H₂(OCH₃)2CH₂NH₂Pd(P(C₆H₅)3)Br)] 
• 1357295-71-6 1-(2-bromo-4,5-dimethoxybenzyl)-5-(4-methylbenzyl)-3,4-dihydropyridin-2(1H)-one 
• 1357295-82-9 8,9-dimethoxy-1-(4-methylbenzyl)-2,6-dihydropyrido[2,1-a]isoindol-4(3H)-one 
• 1527501-65-0 N-(2-bromo-4,5-dimethoxybenzyl)-4-methylbenzenesulfonamide 
• 1527501-93-4 2,3-dimethoxy-6-tosyl-5,6-dihydroindolo[1,2-a]quinazoline 

Relevant articles and documents

Palladium-Catalyzed α-Arylation of Silylenol Ethers in the Synthesis of Isoquinolines and Phenanthridines

A diverse array of isoquinolines and phenanthridines have been accessed by developing a two-step, one-pot method constituting regioselective palladium-catalyzed Kuwajima-Urabe α-arylation of silylenol ethers and acid-mediated deprotection, annulation, and aromatization. Structural diversity in the silylenol ethers leads to three different classes of isoquinolines and phenanthridines from which related natural products can be derived. The synthetic utility of this method by the quick assembly of the natural product trispheridine is also demonstrated.

CuI-catalyzed coupling of gem-dibromovinylanilides and sulfonamides: An efficient method for the synthesis of 2-amidoindoles and indolo[1,2-a] quinazolines

A Cu(I)-catalyzed, intermolecular protocol for the synthesis of 2-amidoindoles and tetrahydroindolo[1,2-a]quinazolines in shorter time and high yields is reported. The key highlight of this disclosure is the formation of 2-amidoindole and tetrahydroindolo[1,2-a]quinazoline moieties directly from gem-dibromovinylanilides and sulfonamides in a one-pot fashion through the in situ formation of ynamides followed by a base-promoted intramolecular hydroamidation.

Rapid and convergent assembly of natural benzo[c]phenanthridines by palladium/norbornene catalysis

A straightforward total synthesis of a small panel of natural benzo[c]phenanthridines is described. The selective coupling of an aryl triflate with a bromobenzylamine by means of palladium/norbornene joint catalysis and a sequential transfer hydrogenation