89563-44-0

Basic information

• Product Name: Pentanenitrile, 2-bromo-4,4-dimethyl-3-oxo-
• Synonyms: 1-bromo-1-cyano-3,3-dimethylbutan-2-one;Pentanenitrile,2-bromo-4,4-dimethyl-3-oxo
• CAS NO: 89563-44-0
• Molecular Formula: C7H10BrNO
• Molecular Weight: 204.066
• Mol File: 89563-44-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Pentanenitrile, 2-bromo-4,4-dimethyl-3-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanenitrile, 2-bromo-4,4-dimethyl-3-oxo-(89563-44-0)
• EPA Substance Registry System: Pentanenitrile, 2-bromo-4,4-dimethyl-3-oxo-(89563-44-0)

Safety Data

• Hazardous Substances Data: 89563-44-0(Hazardous Substances Data)

Upstream product

• 59997-51-2 trimethylacetylacetonitrile 

Downstream Products

• 1388852-54-7 2-(2-(2,4-dibromophenoxy)-4,6-dibromophenoxy)-4,4-dimethyl-3-oxopentanenitrile 

Relevant articles and documents

CF3S(O)n-Containing olefins in cyclopropanation reactions

Cyclopropanation of trifluoromethyl(sulfinyl, sulfonyl) ethylenes was achieved by utilization of α-bromo- or α,α-dibromo 1,3-dicarbonyl compounds in the presence of bases. DBU was found to be the best choice to get satisfactory yields of cyclopropanes with CF3S(O)n (n = 1, 2) groups if α-bromo-1,3-dicarbonyl compounds were used. A series of new cyclopropanes bearing trifluoromethylsulfinyl group were synthesized.

THERAPEUTIC AGENT FOR CANCER

A medicament for the prevention and/or treatment of cancers and the like which comprises as an active ingredient a substance selected from the group consisting of a compound represented by the following general formula (I) and a pharmacologically acceptable salt thereof, and a hydrate thereof and a solvate thereof: wherein A represents hydrogen atom or acetyl group, E represents a 2,5-di-substituted or a 3,5-di-substituted phenyl group, or a monocyclic or a fused polycyclic heteroaryl group which may be substituted, provided that the compound wherein said heteroaryl group is 1? a fused polycyclic heteroaryl group wherein the ring which binds directly to ―CONH― group in the formula (I) is a benzene ring, 2? unsubstituted thiazol-2-yl group, or 3? unsubstituted benzothiazol-2-yl group is excluded, ring Z represents an arene which may have one or more substituents in addition to the group represented by formula ―O―A wherein A has the same meaning as that defined above and the group represented by formula ―CONH―E wherein E has the same meaning as that defined above, or a heteroarene which may have one or more substituents in addition to the group represented by formula ―O―A wherein A has the same meaning as that defined above and the group represented by formula ― CONH―E wherein E has the same meaning as that defined above.

THERAPEUTIC DRUG FOR DIABETES

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