89608-07-1

Basic information

• Product Name: 1-(S-α-phenylethyl)-3-(2-cyanoethyl)piperidin-4-one
• CAS NO: 89608-07-1
• Molecular Weight: 256.348
• Mol File: 89608-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(S-α-phenylethyl)-3-(2-cyanoethyl)piperidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(S-α-phenylethyl)-3-(2-cyanoethyl)piperidin-4-one(89608-07-1)
• EPA Substance Registry System: 1-(S-α-phenylethyl)-3-(2-cyanoethyl)piperidin-4-one(89608-07-1)

Safety Data

• Hazardous Substances Data: 89608-07-1(Hazardous Substances Data)

Upstream product

• 89608-20-8 1-(S-α-phenylethyl)-4-pyrrolidino-3-piperideine 
• 107-13-1 acrylonitrile 
• 36482-37-8 N-<(S)-α-methylbenzyl>-4-piperidone 

Relevant articles and documents

SYNTHESIS OF 3-SUBSTITUTED 4-PIPERIDONES

It has been shown that the addition of methyl acrylate and acrylonitrile to the pyrrolidine enamines of 1-methyl-, (1S)-α-phenylethyl-, (1S)-sec-butyl, 1,2-dimethyl, and 1,3-dimethyl-4-piperidone results in the formation of 3- or 5-substituted 4-piperidones, depending on the reaction conditions and the structure of the enamine.The formation of a pair of diastereomers of the 3-substituted 4-piperidones in a 1:1 ratio takes place when there is a chiral substituent on the nitrogen atom in the piperidone ring.