896139-36-9

Basic information

• Product Name: 1-(4-chloropyridin-2-yl)propan-1-one
• Synonyms: 1-(4-chloropyridin-2-yl)propan-1-one
• CAS NO: 896139-36-9
• Molecular Formula: C₈H₈ClNO
• Molecular Weight: 169.60822
• Mol File: 896139-36-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-(4-chloropyridin-2-yl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chloropyridin-2-yl)propan-1-one(896139-36-9)
• EPA Substance Registry System: 1-(4-chloropyridin-2-yl)propan-1-one(896139-36-9)

Safety Data

• Hazardous Substances Data: 896139-36-9(Hazardous Substances Data)

Usage

General Description

1-(4-chloropyridin-2-yl)propan-1-one is a chemical compound with the molecular formula C8H8ClNO. It is a ketone derivative with a pyridine ring and a chlorine atom attached to it. 1-(4-chloropyridin-2-yl)propan-1-one is commonly used in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a building block for the development of new organic molecules and materials. 1-(4-chloropyridin-2-yl)propan-1-one has various potential applications in the fields of medicinal chemistry, drug discovery, and materials science, making it an important intermediate in chemical synthesis.

Upstream product

• 19235-89-3 4-chloro-pyridine-2-carbonitrile 
• 925-90-6 ethylmagnesium bromide 
• 1121-76-2 4-chloropyridine N-oxide 

Relevant articles and documents

Engineering an iridium-containing metal-organic molecular capsule for induced-fit geometrical conversion and dual catalysis

By introducing photoactive fac-tris(2-phenylpyridine)iridium moieties as a ligand backbone to constrain the coordination geometry of cobalt ions, a multifunctional Ir2Co3-type capsule was achieved and showed induced-fit capsule-capsule conversion by cooperative binding one carbonate anion with the equatorial Co(ii) centers. The capsule combined photocatalysis and transition metal activation synergistically and exhibited efficient catalytic ability on visible light-activated α-trichloromethylation.

Biocatalytic preparation of optically active 4-(N,N-dimethylamino)pyridines for application in chemical asymmetric catalysis

4-Chloro-2-(1-hydroxybenzyl)pyridine and 4-chloro-2-(1-hydroxyalkyl)pyridines were obtained with moderate to excellent enantiomeric excesses and high isolated yields by bioreduction with Baker's yeast of the corresponding ketones. The resulting optically active alcohols were transformed into adequate DMAP derivatives, which have been applied in asymmetric catalytic processes as nucleophilic catalysts in the stereoselective chemical alkoxycarbonylation of 1-phenylethanol or as chiral ligands in the enantioselective addition of diethylzinc to benzaldehyde.