89722-87-2Relevant articles and documents
3-FLUOROBENZODIAZEPINES
Middleton, W. J.,Bingham, E. M.,Smith, D. H.
, p. 557 - 572 (2007/10/02)
Benzodiazepines that bear a fluorine substituent in the metabolically active C-3 position were prepared by the reaction of diethylaminosulfur trifluoride (DAST) with the corresponding 3-hydroxybenzodiazepines.These products are surprisingly stable to hydrolysis and possess potent antianxiety and muscle-relaxing properties.