897446-33-2

Basic information

• Product Name: 4'-fluorobiphenyl-2-carboxylic acid (2-aminophenyl)amide
• CAS NO: 897446-33-2
• Molecular Weight: 306.339
• Mol File: 897446-33-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-fluorobiphenyl-2-carboxylic acid (2-aminophenyl)amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-fluorobiphenyl-2-carboxylic acid (2-aminophenyl)amide(897446-33-2)
• EPA Substance Registry System: 4'-fluorobiphenyl-2-carboxylic acid (2-aminophenyl)amide(897446-33-2)

Safety Data

• Hazardous Substances Data: 897446-33-2(Hazardous Substances Data)

Upstream product

• 80254-82-6 methyl 4'-fluoro-[1,1'-biphenyl]-2-carboxylate 
• 1765-93-1 4-fluoroboronic acid 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 1841-57-2 4’-fluoro-[1,1’-biphenyl]-2-carboxylic acid 
• 95-54-5 1,2-diamino-benzene 

Relevant articles and documents

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

Design, synthesis and structure-activity relationships of benzimidazole derivatives as activators of the AMP-activated protein kinase (AMPK) are presented in this paper. AMPK is the central component of a protein kinase cascade that plays a key role in the regulation of energy balance. Once activated, AMPK initiates a series of responses that are aimed at restoring the energy balance of the cell and recent studies have indicated that AMPK plays an important role in regulation of the whole-body energy metabolism. The following study based on the lead compound S27847 involved modification of three regions of this compound. Preliminary structure-activity relationships are being described.