897961-91-0

Basic information

• Product Name: (S)-2-(((4-bromobenzyl)oxy)methyl)oxirane
• Synonyms: (S)-2-(((4-bromobenzyl)oxy)methyl)oxirane
• CAS NO: 897961-91-0
• Molecular Weight: 243.1
• Mol File: 897961-91-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(((4-bromobenzyl)oxy)methyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(((4-bromobenzyl)oxy)methyl)oxirane(897961-91-0)
• EPA Substance Registry System: (S)-2-(((4-bromobenzyl)oxy)methyl)oxirane(897961-91-0)

Safety Data

• Hazardous Substances Data: 897961-91-0(Hazardous Substances Data)

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 57044-25-4 (R)-oxiranemethanol 

Downstream Products

• 897961-92-1 (2S)-1-(4-bromo-benzyloxy)-5-trimethylsilanyl-pent-4-yn-2-ol 
• 897961-34-1 (2''S)-1-{2-[3-(4-bromobenzyloxy)-2-triethylsilanyloxy-propyl][1,3]dithian-2-yl}-6,7-dihydroxy-heptan-2-one 
• 897961-32-9 (2S)-1-(4-bromobenzyloxy)-10,11-dihydroxy-2-triethylsilanyloxyundec-4-yn-6-one 
• 897961-30-7 (10S)-11-(4-bromobenzyloxy)-10-triethylsilanyloxyundec-1-en-7-yn-6-one 
• 897961-28-3 (10S)-11-(4-bromobenzyloxy)-10-triethylsilanyloxyundec-1-en-7-yn-6-ol 
• 897961-26-1 (5S)-6-(4-bromo-benzyloxy)-5-triethylsilanyloxy-hex-2-ynal 
• 897961-95-4 (1S)-[1-(4-bromo-benzyloxymethyl)-but-3-ynyloxy]-triethyl-silane 
• 897961-93-2 (2S)-1-(4-bromo-benzyloxy)-pent-4-yn-2-ol 

Relevant articles and documents

Substrate stereocontrol in bromine-induced intermolecular cyclization: Asymmetric synthesis of pitavastatin calcium

A novel approach to synthesize pitavastatin calcium (1), an effective HMG-CoA reductase inhibitor, based on readily available and attractively functionalized (R)-3-chloro-1,2-propanediol is reported. This work highlights an intermolecular diastereoselective bromine-induced cyclization of homoallylic carbonate to meet stereochemical challenges in the synthesis of statins. An efficient route to a new triphenylphosphonium tetrafluoroborate salt of a quinoline core is also presented.