898533-23-8

Basic information

• Product Name: 4-(4-(3-methoxyphenyl)piperazin-1-yl)butan-1-amine
• Synonyms: 4-(4-(3-methoxyphenyl)piperazin-1-yl)butan-1-amine
• CAS NO: 898533-23-8
• Molecular Weight: 263.383
• Mol File: 898533-23-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-(4-(3-methoxyphenyl)piperazin-1-yl)butan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(3-methoxyphenyl)piperazin-1-yl)butan-1-amine(898533-23-8)
• EPA Substance Registry System: 4-(4-(3-methoxyphenyl)piperazin-1-yl)butan-1-amine(898533-23-8)

Safety Data

• Hazardous Substances Data: 898533-23-8(Hazardous Substances Data)

Upstream product

• 6968-76-9 1-(3-methoxyphenyl)piperazine dihydrochloride 
• 898533-22-7 4-[4-(3-methoxyphenyl)piperazin-1-yl]butanenitrile 

Downstream Products

• 1137920-29-6 N-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-2,1,3-benzoxadiazole-5-carboxamide 
• 898533-24-9 N-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-3-carboxamide 

Relevant articles and documents

Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands

As part of our on-going effort to explore the role of dopamine receptors in drug addiction and identify potential novel therapies for this condition, we have a identified a series of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamide D3 ligands. Members of this class are highly selective for D3 versus D2, and we have identified two compounds (13g and 13r) whose rat in vivo IV pharmacokinetic properties that indicate that they are suitable for assessment in in vivo efficacy models of substance use disorders.

Novel Aryl Piperazine Derivatives With Medical Utility

This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, D2-like and 5-HT2 receptor subtypes, and in particular u