89873-78-9

Basic information

• Product Name: Pyridine, 1,2,3,6-tetrahydro-2-methyl-1-(phenylmethyl)-
• CAS NO: 89873-78-9
• Molecular Formula: C13H17N
• Molecular Weight: 187.285
• Mol File: 89873-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyridine, 1,2,3,6-tetrahydro-2-methyl-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 1,2,3,6-tetrahydro-2-methyl-1-(phenylmethyl)-(89873-78-9)
• EPA Substance Registry System: Pyridine, 1,2,3,6-tetrahydro-2-methyl-1-(phenylmethyl)-(89873-78-9)

Safety Data

• Hazardous Substances Data: 89873-78-9(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 109-06-8 α-picoline 
• 13686-87-8 1-benzyl-2-methylpyridinium chloride 
• 2654-66-2 1-Benzyl-6-methylpyridinium bromide 

Downstream Products

• 89873-77-8 1-Benzyl-cis-2-propyl-6-methyl-4-piperideine 
• 89873-76-7 1-Benzyl-trans-2-propyl-6-methyl-4-piperideine 
• 89873-75-6 1-Benzyl-cis-2-propyl-6-methyl-3-piperideine 
• 89873-74-5 (+/-)-trans-1-benzyl-2-methyl-6-propyl-1,2,3,6-tetrahydropyridine 
• 89873-66-5 cis-1-Benzyl-2-cyano-6-methylpiperidine 
• 89873-65-4 trans-1-benzyl-6-methylpiperidine-2-carbonitrile 
• 84268-83-7 1-Benzyl-2-cyano-6-methyl-3-piperideine 
• 89873-73-4 1-Benzyl-6-methyl-2-propyl-1,2,5,6-tetrahydro-pyridine-2-carbonitrile 
• 89873-52-9 1-Benzyl-6-methyl-1,2,5,6-tetrahydropyridine N-oxide 

Relevant articles and documents

COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF

Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, psychiatric disorders, neuromuscular disorders, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds provided herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

2-Cyano-Δ3-piperideines. 12. Stereochemistry of Formation of N-Benzyl-2-cyano-Δ3-piperideines and Facile Isomerization on Alumina to 2-Cyano-Δ4-piperideines. A Potentially General Route to the Synthesis of 2,6-Disubstitute

The reaction of the piperideine N-oxides 1a-f with trifluoroacetic anhydride in CH2Cl2 at 0 deg C (Polonovski-Potier reaction) led to the formation of the N-benzyl-2-cyano-Δ3-piperideines 3a-f.Epimeric mixtures were obtained for the amino nitri