898746-82-2Relevant articles and documents
Rapid access to spirocyclic oxindole alkaloids: Application of the asymmetric palladium-catalyzed [3 + 2] trimethylenemethane cycloaddition
Trost, Barry M.,Bringley, Dustin A.,Zhang, Ting,Cramer, Nicolai
, p. 16720 - 16735 (2013)
The marcfortines are complex secondary metabolites that show potent anthelmintic activity and are characterized by the presence of a bicyclo[2.2.2]diazaoctane fused to a spirooxindole. Herein, we report the synthesis of two members of this family. The syn
P300/CBP HAT INHIBITORS
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, (2019/09/04)
Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with histone acetyltransferase (HAT).
Concise, asymmetric, stereocontrolled total synthesis of stephacidins A, B and notoamide B
Artman III, Gerald D.,Grubbs, Alan W.,Williams, Robert M.
, p. 6336 - 6342 (2008/02/03)
Concise asymmetric total syntheses of the fungal metabolites (-)-stephacidin A, (+)-stephacidin B, and (+)-notoamide B are described. Key features of these total syntheses include (1) a facile synthesis of (R)-allyl proline methyl ester, (2) a revised rou