898798-67-9

Basic information

• Product Name: 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 2-cyano-ethyl ester
• Synonyms: 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 2-cyano-ethyl ester
• CAS NO: 898798-67-9
• Molecular Weight: 330.3
• Mol File: 898798-67-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 2-cyano-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 2-cyano-ethyl ester(898798-67-9)
• EPA Substance Registry System: 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 2-cyano-ethyl ester(898798-67-9)

Safety Data

• Hazardous Substances Data: 898798-67-9(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 65193-87-5 2-cyanoethylacetoacetate 
• 57-13-6 urea 

Downstream Products

• 123371-45-9 ethyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 
• 296267-03-3 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid cyclopentyl ester 
• 295344-04-6 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 2-ethylsulfanyl-ethyl ester 
• 356566-57-9 6-methyl-4-(4-nitro-phenyl)-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid 

Relevant articles and documents

Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4

Several potent, cell permeable 4-aryl-dihydropyrimidinones have been identified as inhibitors of FATP4. Lipophilic ester substituents at the 5-position and substitution at the para-position (optimal groups being -NO2 and CF3) of the 4-aryl group led to active compounds. In two cases racemates were resolved and the S enantiomers shown to have higher potencies.