89894-23-5

Basic information

• Product Name: 4-(4-chlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-ol
• CAS NO: 89894-23-5
• Molecular Weight: 227.674
• Mol File: 89894-23-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-ol(89894-23-5)
• EPA Substance Registry System: 4-(4-chlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-ol(89894-23-5)

Safety Data

• Hazardous Substances Data: 89894-23-5(Hazardous Substances Data)

Upstream product

• 22814-92-2 4-(p-chlorophenyl)-3-thiosemicarbazide 
• 105-58-8 Diethyl carbonate 
• 134832-82-9 C₁₅H₁₄ClN₃OS₂ 
• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 119416-47-6 3-(4-chloro-phenylthiocarbamoyl)-carbazic acid ethyl ester 

Downstream Products

• 134832-78-3 5-Benzylsulfanyl-4-(4-chloro-phenyl)-4H-[1,2,4]triazol-3-ol 

Relevant articles and documents

Thiocarbazinic acids: Interaction of carbonoxysulphide with thiosemicarbazides - Synthesis of &β-(thiocarbamyl)thiocarbazinates and 1,3,4-oxadiazole and 1,2,4-triazole derivatives

Interaction of carbon oxysulphide with 4-alkyl/arylthiosemicarbazides (I) in ethanol in the presence of sodium hydroxide forms sodium β-(N-alkyl/arylthiocarbamyl)thiocarbazinates (II).Benzylation of the latter (II) affords 5-alkyl/arylamino-2-benzylmercapto-1,3,4-oxadiazoles (IV), which can also be obtained by a one-pot synthesis involving the reaction of I with carbon oxysulphide in DMF in the presence of triethylamine and benzyl chloride.The syntheses of benzyl β-(N-alkyl/arylthiocarbamyl)thiocarbazinates (III) and 4-aryl-3-mercapto-1,2,4-triazolin-5-ones (VII) are also reported.Some of the compounds exhibit antibacterial activity.