89901-01-9

Basic information

• Product Name: [1,1-BIPHENYL]-4-CARBOXYLIC ACID, 3-CHLORO-, METHYL ESTER
• Synonyms: [1,1-BIPHENYL]-4-CARBOXYLIC ACID, 3-CHLORO-, METHYL ESTER
• CAS NO: 89901-01-9
• Molecular Formula: C14H11ClO2
• Molecular Weight: 246.693
• Mol File: 89901-01-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: [1,1-BIPHENYL]-4-CARBOXYLIC ACID, 3-CHLORO-, METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1-BIPHENYL]-4-CARBOXYLIC ACID, 3-CHLORO-, METHYL ESTER(89901-01-9)
• EPA Substance Registry System: [1,1-BIPHENYL]-4-CARBOXYLIC ACID, 3-CHLORO-, METHYL ESTER(89901-01-9)

Safety Data

• Hazardous Substances Data: 89901-01-9(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 5728-43-8 3'-chloro-[1,1'-biphenyl]-4-carboxylic acid 
• 108-90-7 chlorobenzene 
• 1571-08-0 methyl 4-formylbenzoate 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 63503-60-6 3-chlorophenylboronic acid 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 

Downstream Products

• 5728-43-8 3'-chloro-[1,1'-biphenyl]-4-carboxylic acid 

Relevant articles and documents

Cobalt-catalyzed cross-coupling reactions of aryl- And alkylaluminum derivatives with (hetero)aryl and alkyl bromides

A simple cobalt complex, such as Co(phen)Cl2, turned out to be a highly efficient and cheap precatalyst for a host of cross-coupling reactions involving aromatic and aliphatic organoaluminum reagents with aryl, heteroaryl and alkyl bromides. New C(sp2)-C(sp2) and C(sp2)-C(sp3) bonds were formed in good to excellent yields and with high chemoselectivity, under mild reaction conditions.

Metal-free iodination of arylboronic acids and the synthesis of biaryl derivatives

A simple, general and efficient method is developed for the metal-free iodination of arylboronic acids. The protocol uses very cheap molecular iodine as the halide source and potassium carbonate as the base. The method is highly tolerant of various functional groups present in the substrates. Importantly, the iodination strategy can also be applied very effectively in the one-pot, two-step synthesis of biaryl derivatives. Georg Thieme Verlag Stuttgart New York.

The Effects of Substituents on the Rate of Saponification of Biphenyl-4-carboxylates

Second-order rate constants have been measured for the saponification of methyl 2'-, 3'-, and 4'-substituted biphenyl-4-carboxylates at several temperatures in 85percent (w/w) methanol-water and activation parameters have been calculated.The Hammett equation applies very well to the saponification of 3'- and 4'-substituted biphenyl-4-carboxylates with ?-constants evaluated by the FMMF method.The effect of 2'-substituents is understandable in terms of ?-electron steric effects.