89938-07-8

Basic information

• Product Name: 2,4-dichloro-6-propyl-pyrimidine
• Synonyms: 2,4-dichloro-6-propyl-pyrimidine;2,6-dichloro-4-n-propylpyrimidine;PyriMidine, 2,4-dichloro-6-propyl-
• CAS NO: 89938-07-8
• Molecular Formula: C₇H₈Cl₂N₂
• Molecular Weight: 191.06
• Mol File: 89938-07-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 261.8 °C at 760 mmHg
• Flash Point: 137.5 °C
• Appearance: /
• Density: 1.281 g/cm³
• Vapor Pressure: 0.0184mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: 2-8°C
• PKA: -2.12±0.30(Predicted)
• CAS DataBase Reference: 2,4-dichloro-6-propyl-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-6-propyl-pyrimidine(89938-07-8)
• EPA Substance Registry System: 2,4-dichloro-6-propyl-pyrimidine(89938-07-8)

Safety Data

• Hazardous Substances Data: 89938-07-8(Hazardous Substances Data)

Usage

General Description

2,4-dichloro-6-propyl-pyrimidine is a chemical compound with the molecular formula C7H8Cl2N2. It belongs to the class of pyrimidine compounds and is characterized by the presence of two chlorine atoms and a propyl group attached to the pyrimidine ring. 2,4-dichloro-6-propyl-pyrimidine has a wide range of applications in the field of agrochemicals as a herbicide and fungicide. It is also used in the synthesis of pharmaceuticals and other organic compounds. 2,4-dichloro-6-propyl-pyrimidine is a highly reactive and versatile compound that has gained importance in various industrial and research applications.

InChI:InChI=1/C7H8Cl2N2/c1-2-3-5-4-6(8)11-7(9)10-5/h4H,2-3H2,1H3

Upstream product

• 13345-08-9 6-propyl(1H,3H)pyrimidine-2,4-dione 
• 3934-20-1 2,6-Dichloropyrimidine 
• 2417-93-8 propyllithium 
• 51-52-5 propylthiouracil 
• 3249-68-1 ethyl butyroyl acetate 

Downstream Products

• 887496-20-0 4-chloro-6-propyl-2-[4-(4-trifluoromethoxy-phenyl)-imidazol-1-yl]-pyrimidine 
• 684220-67-5 4-chloro-6-propyl-2-[4-(3-trifluoromethoxyphenyl)-imidazol-1-yl]-pyrimidine 
• 73576-45-1 4-(2,4-Diamino-6-propyl-pyrimidin-5-ylmethyl)-2,6-dimethoxy-phenol 
• 73576-25-7 6-Propyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,4-diamine 
• 1394321-66-4 (S)-2-chloro-4-[2-(methoxymethyl)pyrrolidin-1-yl]-6-propylpyrimidine 
• 1394320-64-9 (S)-N₁-{4-[3-(methylamino)pyrrolidin-1-yl]-6-propylpyrimidin-2-yl}-3-(trifluoromethyl)benzene-1,4-diamine 
• 1394316-04-1 (R)-2-methyl-5-[4-(2-methylpyrrolidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile hydrochloride 
• 1394316-78-9 (S)-N-{1-[2-(4-chloro-3-nitrophenylamino)-6-propylpyrimidin-4-yl]pyrrolidin-3-yl}acetamide 
• 1394316-97-2 (S)-N-{1-[2-(4-amino-3-cyanophenylamino)-6-propylpyrimidin-4-yl]pyrrolidin-3-yl}acetamide hydrochloride 
• 1394317-79-3 (R)-2-methyl-5-[4-(2-methylpyrrolidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile 
• 1394320-92-3 (S)-N₁-[4-(3-aminopyrrolidin-1-yl)-6-propylpyrimidin-2-yl]-5-(trifluoromethyl)benzene-1,3-diamine 
• 1394318-58-1 (S)-3-amino-5-{[4-(3-aminopyrrolidin-1-yl)-6-propylpyrimidin-2-yl]amino}benzonitrile 
• 1394803-37-2 2-{1-[2-(4-chloro-3-nitrophenylamino)-6-propylpyrimidin-4-yl]piperidin-2-yl}ethanol 
• 1394803-96-3 4-morpholino-N-(3-nitrophenyl)-6-propylpyrimidin-2-amine hydrochloride 

Relevant articles and documents

HEPATITIS B VIRAL ASSEMBLY EFFECTORS

Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV.

DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HT4 receptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.

DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HT4 receptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.