89943-14-6

Basic information

• Product Name: 2-HYDROXY-2-PYRIDYL ETHYLAMINE
• Synonyms: 2-AMINO-1-PYRIDIN-2-YL-ETHANOL;2-HYDROXY-2-PYRIDYL ETHYLAMINE;2-AMINO-1-(2-PYRIDINYL)ETHANOL;a-(aMinoMethyl)-2-PyridineMethanol;2-Amino-1-(pyridin-2-yl)ethan-1-ol
• CAS NO: 89943-14-6
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• Product Categories: pharmacetical
• Mol File: 89943-14-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-HYDROXY-2-PYRIDYL ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXY-2-PYRIDYL ETHYLAMINE(89943-14-6)
• EPA Substance Registry System: 2-HYDROXY-2-PYRIDYL ETHYLAMINE(89943-14-6)

Safety Data

• Hazardous Substances Data: 89943-14-6(Hazardous Substances Data)

Usage

General Description

2-Hydroxy-2-pyridyl ethylamine, also known as HPEA, is a chemical compound primarily used in the pharmaceutical industry as a chelating agent. It is commonly used to sequester metal ions in biological systems, particularly copper, which is crucial for the regulation of physiological processes. HPEA has also shown potential as a therapeutic agent for treating diseases associated with copper toxicity, such as Wilson's disease and various neurodegenerative disorders. Additionally, it has been studied for its potential antioxidant and anti-inflammatory properties, making it a promising molecule for future drug development. However, further research is needed to fully understand its biological effects and potential clinical applications.

Upstream product

• 51746-81-7 2-amino-1-[2]pyridyl-ethanone; dihydrochloride 
• 14255-55-1 2-nitro-1-(2-pyridyl)ethanol 
• 1121-60-4 pyridine-2-carbaldehyde 

Downstream Products

• 2706-56-1 2-(aminoethyl)pyridine 

Relevant articles and documents

Easy kinetic resolution of some β-amino alcohols by Candida antarctica lipase B catalyzed hydrolysis in organic media

Herein, we present an easy and eco-friendly pathway to obtain some enantiomerically enriched β-amino alcohols using essentially as β-blockers. The enzymatic hydrolysis is conducted in hydrophobic organic media, assisted by sodium carbonate and CAL-B. We describe a new and effective procedure in terms of the chemo- and enantioselectivity, which allows for the formation of both enantiomers: the 2-acetamido-1-arylacetates and 2-acetamido-1-arylethanols were obtained with high ee values (up to >99%), while the selectivities reached E >200. The obtained results show a high CAL-B affinity toward the deacylation of the 2-acetamido-1-arylacetates compared to the acylation one. The structure of the 2-acetamido-1-arylacetates had a significant influence on both reactivity and selectivity of the CAL-B catalyzed deacylation. A multigram scale O-deacylation of racemic 2-acetamido-1-phenylacetate has been carried out, giving access both enantiomers with high enantiomeric purity and good isolated chemical yields.

Oxazinoquinolones useful for the treatment of viral infections

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.