89977-04-8Relevant articles and documents
New synthons for the synthesis of lanthanide containing macrocyclic schiff bases featuring substituents available for tethering
Dumont, Arnaud,Jacques, Vincent,Desreux, Jean F.
, p. 2043 - 2052 (2007/10/03)
2,6-Diacetylpyridine substituted with amine or alcohol groups in the 4- position have been prepared from chelidamic acid. The key 4-chloro derivative was synthesized in high yield via a diazo intermediate and was protected as a bis-1,3-dioxane before substitution with various amino alcohol groups. Lanthanide macrocyclic tetra-imine complexes were obtained by a template procedure that leads to stable paramagnetic and/or fluorescent derivatives with anchor groups available for linkage to macromolecules. (C) 2000 Elsevier Science Ltd.