899809-74-6

Basic information

• Product Name: Vorapaxar
• Synonyms: ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate; carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester; Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]vinyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate; SCH 530348; TRA-SCH 530348
• CAS NO: 899809-74-6
• Molecular Formula: C₁₇H₁₅NO₂
• Molecular Weight: 492.5817
• Mol File: 899809-74-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 676°C at 760 mmHg
• Flash Point: 362.632°C
• Density: 1.25g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: Vorapaxar(CAS DataBase Reference)
• NIST Chemistry Reference: Vorapaxar(899809-74-6)
• EPA Substance Registry System: Vorapaxar(899809-74-6)

Safety Data

• Hazardous Substances Data: 899809-74-6(Hazardous Substances Data)

Upstream product

• 899809-75-7 C₁₉H₁₇NO₃ 

Downstream Products

• 1017854-08-8 C₂₆H₂₄N₂O₅ 
• 899809-78-0 C₂₄H₂₁NO₄S 

Relevant articles and documents

Thrombin Receptor Antagonists Based On The Modified Tricyclic Unit Of Himbacine

Multiple stereoisomers of the heterocyclic-substituted tricyclics of the formula: or a pharmaceutically acceptable salt, solvate, or ester of said compound wherein R and the stereochemistry are illustrated in the structural formulas herein are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. Combination therapy with other cardiovascular agents is also claimed.