89981-01-1Relevant articles and documents
Palladium-Catalyzed C-S Bond Formation as a Tool for Latent-Active Glycosylation
Hedberg, Christinne,Jessen, Kamilla S.,Hansson, Rikke F.,Heuckendorff, Mads,Jensen, Henrik H.
, p. 7068 - 7072 (2020/10/02)
A high-yielding palladium-catalyzed C-S cross-coupling is presented for utilization in carbohydrate chemistry as a key transformation for attachment of a second chelating sulfur atom that allows the exploitation of a latent-active glycosylation strategy w
Syntheses, structures, and catalytic activities of hemilabile thioether-functionalized NHC complexes
Huynh, Han Vinh,Yeo, Chun Hui,Chew, Ying Xia
experimental part, p. 1479 - 1486 (2010/05/15)
Four imidazolium (5a/b) and benzimidazolium (6a/b) salts with hemilabile alkyl-aryl thioether functions have been prepared via a straightforward and modular pathway in order to compare their reactivities toward palladation. Reaction of 5a/b with Pd(OAc)s
5-Benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators
Zhi, Lin,Tegley, Christopher M.,Pio, Barbara,Edwards, James P.,Motamedi, Mehrnouch,Jones, Todd K.,Marschke, Keith B.,Mais, Dale E.,Risek, Boris,Schrader, William T.
, p. 4104 - 4112 (2007/10/03)
A series of 5-benylidene-1,2-dihydrochromeno[3,4-f]quinolines (4) were synthesized and tested in bioassays to evaluate their progestational activities, receptor- and tissue-selectivity profiles as selective progesterone receptor modulators (SPRMs). Most of the new analogues exhibited as highly potent progestins with more than 100-fold receptor selectivity over other steroid hormone receptors and LG120920 (7b) demonstrated tissue selectivity toward uterus and vagina versus breasts in a rodent model after oral administration.
