899818-48-5Relevant articles and documents
Isatin sulfonamide analogs containing a Michael addition acceptor: A new class of caspase 3/7 inhibitors
Chu, Wenhua,Rothfuss, Justin,D'Avignon, André,Zeng, Chenbo,Zhou, Dong,Hotchkiss, Richard S.,Mach, Robert H.
, p. 3751 - 3755 (2007)
A series of isatin sulfonamide analogs having a Michael acceptor were prepared and their potencies for inhibiting caspase-1, -3, -6, -7, and -8 were evaluated. These compounds have nanomolar potency for inhibiting the executioner caspases, caspase-3 and c
5-PYRROLIDINYLSULFONYL ISATIN DERIVATIVES
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Page/Page column 37-38, (2008/06/13)
The present invention relates to novel 5-pyrrolidinylsulfonyl isatin derivatives, non-peptidyl Caspase binding Radioligands (CbRs) and CbR-transporter conjugates derived from said isatin derivatives, diagnostic compositions comprising said compounds of th