90-60-8

Basic information

• Product Name: 3,5-DICHLOROSALICYLALDEHYDE
• Synonyms: Benzaldehyde,3,5-dichloro-2-hydroxy-;Salicylaldehyde, 3,5-dichloro-;Salicylaldehyde,3,5-dichloro-;AKOS B029257;3,5-DICHLORO SALICYLAL;3,5-DICHLOROSALICYLALDEHYDE;3,5-DICHLORO-2-HYDROXYBENZALDEHYDE;LABOTEST-BB LT00089371
• CAS NO: 90-60-8
• Molecular Formula: C₇H₄Cl₂O₂
• Molecular Weight: 191.01
• EINECS: 202-005-5
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;Aldehydes;C7;Carbonyl Compounds
• Mol File: 90-60-8.mol
• Article Data: 19

Chemical Properties

• Melting Point: 95-97 °C(lit.)
• Boiling Point: 273.68°C (rough estimate)
• Flash Point: 96.9 °C
• Appearance: Pale yellow/Crystalline Powder
• Density: 1.4410 (rough estimate)
• Vapor Pressure: 0.0304mmHg at 25°C
• Refractive Index: 1.4590 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: ethanol: soluble5%, clear, faintly yellow to greenish-yellow
• PKA: 6.27±0.23(Predicted)
• Water Solubility: Insoluble in water. Solubility in methanol is almost transparent.
• Sensitive: Air Sensitive
• BRN: 973391
• CAS DataBase Reference: 3,5-DICHLOROSALICYLALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICHLOROSALICYLALDEHYDE(90-60-8)
• EPA Substance Registry System: 3,5-DICHLOROSALICYLALDEHYDE(90-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 90-60-8(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 90-60-8 differently. You can refer to the following data:
1. 3,5-Dichlorosalicylaldehyde has been used in the preparation of Schiff base ligands and (RS)-3,5-dichloro-2-[[(1-phenylethyl)imino]methyl]phenol.
2. 3,5-Dichlorosalicylaldehyde has been used in the preparation of:Schiff base ligands(RS)-3,5-dichloro-2-[[(1-phenylethyl)imino]methyl]phenol

InChI:InChI=1/C7H4Cl2O2/c8-5-1-4(3-10)7(11)6(9)2-5/h1-3,11H

Upstream product

• 64-17-5 ethanol 
• 100-97-0 hexamethylenetetramine 
• 120-83-2 2,4-dichlorophenol 
• 6641-02-7 3,5-dichloro-2-hydroxybenzyl alcohol 
• 127-68-4 sodium 3-nitrobenzenesulfonate 
• 6333-33-1 2,4-dichloro-6-(chloromethyl)phenol 
• 855156-83-1 bis-(3,5-dichloro-2-hydroxy-benzyl)-ether 
• 90-02-8 salicylaldehyde 
• 67-66-3 chloroform 
• 7782-50-5 chlorine 
• 64-19-7 acetic acid 
• 13460-50-9 metaboric acid 
• 56-81-5 glycerol 
• 75-75-2 methanesulfonic acid 

Downstream Products

• 96460-25-2 1-<3,5-dichlorosalicylidene>-2-hydrazine 
• 107919-17-5 N-(3,5-dichloro-2-hydroxy-benzylidene)-sulfanilic acid-[2]pyridylamide 
• 2199-91-9 3-acetyl-6,8-dichloro-2H-1-benzopyran-2-one 
• 93203-72-6 3,5,4'-trichloro-2-hydroxy-trans-chalcone 
• 14817-67-5 4-(3,5-dichloro-2-hydroxy-benzylidenamino)-2-hydroxy-benzoic acid 
• 77463-79-7 6,6'-((1E,1'E)-(ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))bis(2,4-dichlorophenol) 
• 52828-99-6 2-(1H-benzoimidazol-2-yl)-4,6-dichloro-phenol 
• 79319-60-1 (E)-2,4-dichloro-6-(((2-hydroxyphenyl)imino)methyl)phenol 
• 14897-93-9 4-(3,5-dichloro-2-hydroxy-benzylidenamino)-benzoic acid ethyl ester 
• 99515-71-6 2,4-dichloro-6-(4,6-dichloro-1H-benzimidazol-2-yl)-phenol 

Relevant articles and documents

Phosphine-catalyzed sequential (2+3)/(2+4) annulation of γ-vinyl allenoates: Access to the synthesis of chromeno[4,3-: B] pyrroles

A phosphine-catalyzed cascade (2+3)/(2+4) cyclization reaction of γ-vinyl allenoates with aldimine esters has been developed to provide a series of chromeno[4,3-b]pyrrole derivatives that contain three contiguous stereogenic centers. The method gives a good yield, excellent chemoselectivity and diastereoselectivity under mild conditions.

Synthesis characterization and cytotoxicity studies of platinum(II) complexes with reduced amino pyridine schiff base and its derivatives as ligands

A series of reduced amino pyridine Schiff base platinum(II) complexes were prepared as potential anticancer drugs, and characterized by NMR, IR spectroscopy, elemental analysis, and molar conductivity. UV and CD results showed the binding mode between these compounds and salmon sperm DNA may be intercalation. The cytotoxicity of these complexes was validated against A549, Hela, and MCF-7 cell lines by MTT assay. Some complexes exhibited better cytotoxic activity than cisplatin against Hela and MCF-7 cell lines.

NO-RELEASING NITROOXY-CHROMENE CONJUGATES

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