90-63-1

Basic information

• Product Name: 1-hydroxy-1-phenylacetone
• Synonyms: 1-hydroxy-1-phenylacetone;L-PHENYL ACETYL CARBINOL;1-hydroxy-1-phenyl-2-propanone;1-hydroxy-1-phenyl-propan-2-one;1-Phenyl-1-hydroxypropane-2-one;Phenylacetylcarbinol;(1S)-1-Hydroxy-1-phenyl-2-propanone;(1S)-1-Phenyl-1-hydroxy-2-propanone
• CAS NO: 90-63-1
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.1745
• EINECS: 202-006-0
• Mol File: 90-63-1.mol
• Article Data: 59

Chemical Properties

• Melting Point: 123-124 °C
• Boiling Point: 253℃
• Flash Point: 105℃
• Appearance: /
• Density: 1.119
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
• PKA: 12.33±0.20(Predicted)
• CAS DataBase Reference: 1-hydroxy-1-phenylacetone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-hydroxy-1-phenylacetone(90-63-1)
• EPA Substance Registry System: 1-hydroxy-1-phenylacetone(90-63-1)

Safety Data

• Hazardous Substances Data: 90-63-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 95, p. 2694, 1973 DOI: 10.1021/ja00789a053Synthetic Communications, 22, p. 1523, 1992 DOI: 10.1080/00397919208021623

InChI:InChI=1/C9H10O2/c1-7(10)9(11)8-5-3-2-4-6-8/h2-6,9,11H,1H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 4410-31-5 (RS)-mandelamide 
• 4304-93-2 2-methyl-1-methoxy-1-phenyl-oxirane 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 135762-75-3 5-phenyl-5-hydroxy-2,4-pentanedione 
• 23022-83-5 1-bromo-1-phenyl-2-propanone 
• 19275-80-0 1-acetoxy-1-phenyl-acetone 
• 5650-40-8 2-hydroxypropiophenone 
• 532-28-5 (RS)-mandelonitrile 
• 5650-44-2 methcathinone 
• 64-19-7 acetic acid 
• 611-71-2 MANDELIC ACID 
• 119-51-7 1-phenyl-1,2-propanedione 2-oxime 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 

Downstream Products

• 5703-17-3 1-phenyl-2-piperidin-1-yl-propan-1-one 
• 101596-63-8 2-methyl-1,4-diphenyl-3-butyne-1,2-diol 
• 93015-37-3 2-methyl-1,3-diphenyl-propane-1,2-diol 
• 26226-58-4 1-Hydroxy-1-phenyl-2-propanone oxime 
• 7624-52-4 (+/-)-1-hydroxy-1-phenyl-acetone semicarbazone 
• 102872-97-9 1-hydroxy-1-phenyl-acetone thiosemicarbazone 
• 20907-13-5 2-methyl-1-phenylpropane-1,2-diol 
• 90925-49-8 2-phenyl-2,3-butanediol 
• 1084-78-2 (1RS,2RS)-(+/-)-1,2-diphenyl-1,2-propandiol 
• 41728-16-9 1,2-diphenylpropan-1,2-diol 
• 40421-52-1 (1RS,2SR)-1-phenylpropane-1,2-diol 
• 20999-77-3 1-phenyl-propane-1,2-dione-2-phenylhydrazone 
• 93734-87-3 1-hydroxy-1-phenyl-acetone-(2,4-dinitro-phenylhydrazone) 
• 90-81-3 ephedrine 

Relevant articles and documents

Zinc salt-catalyzed reduction of α-aryl imino esters, diketones and phenylacetylenes with water as hydrogen source

The zinc salt-catalyzed reduction of α-aryl imino esters, diketones and phenylacetylenes with water as hydrogen source and zinc as reductant was successfully conducted. The presented method provides a low-cost, environmentally friendly and practical preparation of α-aryl amino esters, α-hydroxyketones and phenylethylenes. By using D2O as deuterium source, the corresponding products were obtained in high efficiency with excellent deuterium incorporation rate, which gives a cheap and safe tool for access to valuable deuterium-labelled compounds. This journal is

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