900513-23-7Relevant articles and documents
Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3
Testard, Alexandra,Loge, Cedric,Leger, Benoit,Robert, Jean-Michel,Lozach, Olivier,Blairvacq, Melina,Meijer, Laurent,Thiery, Valerie,Besson, Thierry
, p. 3419 - 3423 (2007/10/03)
In an effort to identify new protein kinase inhibitors with increased potency and selectivity, we have developed the microwave-assisted synthesis of thiazolo[5,4-f]quinazolin-9-ones. The effects of eighteen derivatives on CDK1/cyclin B, CDK5/p25, and GSK-