90084-67-6

Basic information

• Product Name: Hydrazine, 1-(3-bromophenyl)-1-methyl-
• Synonyms: 1-Methyl-1-(3-brom-phenyl)-hydrazin;N-(3-Bromo-phenyl)-N-methyl-hydrazine
• CAS NO: 90084-67-6
• Molecular Formula: C7H9BrN2
• Molecular Weight: 201.066
• Mol File: 90084-67-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Hydrazine, 1-(3-bromophenyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine, 1-(3-bromophenyl)-1-methyl-(90084-67-6)
• EPA Substance Registry System: Hydrazine, 1-(3-bromophenyl)-1-methyl-(90084-67-6)

Safety Data

• Hazardous Substances Data: 90084-67-6(Hazardous Substances Data)

Upstream product

• 66584-32-5 3-bromo-N-methylaniline 
• 17405-06-0 N-(3-bromophenyl)-N-methylnitrous amide 
• 27246-81-7 3-bromophenylhydrazine hydrochloride 
• 74-88-4 methyl iodide 

Downstream Products

• 847606-91-1 C₁₅H₁₂BrClF₃N₃O 
• 847606-92-2 N-[4-chloro-3-(trifluoromethyl)phenyl]-2-methyl-2-(3-pyrimidin-5-ylphenyl)hydrazinecarboxamide 

Relevant articles and documents

Access to the Cinnoline Scaffold via Rhodium-Catalyzed Intermolecular Cyclization under Mild Conditions

Herein, we report Rh(III)-catalyzed, N-amino (hydrazine)-directed C-H functionalization with α-diazo-β-ketoesters for access to the cinnoline scaffold. A diverse set of nondiscriminating conditions obtained for a highly efficient test transformation prompted use of a substrate-replacement technique for an in-depth search of experimental parameter space and pinpointing of the optimized conditions. A successive C-H activation/C-C coupling/intramolecular dehydration mechanistic sequence is proposed. The ability to perform gram-scale synthesis proves the synthetic utility of this simple, yet efficient, method.

Rh(iii)-catalyzed, hydrazine-directed C-H functionalization with 1-alkynylcyclobutanols: A new strategy for 1: H -indazoles

Rh(iii)-catalyzed coupling of phenylhydrazines with 1-alkynylcyclobutanols was realized through a hydrazine-directed C-H functionalization pathway. This [4+1] annulation, based on the cleavage of a Csp-Csp triple bond in alkynylcyclobutanol, provides a new pathway to prepare diverse 1H-indazoles under mild reaction conditions. This journal is

C-KIT MODULATORS AND METHODS OF USE

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention