901126-79-2Relevant articles and documents
Studies related to the relative thermodynamic stability of C-terminal peptidyl esters of O-hydroxy thiophenol: Emergence of a doable strategy for non-cysteine ligation applicable to the chemical synthesis of glycopeptides
Chen, Gong,David Warren,Chen, Jiehao,Wu, Bin,Wan, Qian,Danishefsky, Samuel J.
, p. 7460 - 7462 (2007/10/03)
A pathway has been devised, wherein a phenolic ester of a C-terminal peptide is ligated with an N-terminal peptide through two consecutive acyl migrations. In the first transacylation, the C-terminus is transferred from a phenol to a newly liberated ortho