90134-00-2 Usage
Description
DI-4-ANEPPS is a potentiometric fluorescent dye that can be used to measure membrane potential. It displays absorption/emission maxima of 495/705 nm, respectively. The relative fluorescence changes proportionally to membrane potential at a rate of approximately 10% per 100 mV. DI-4-ANEPPS has been used to measure membrane potential in a variety of tissue and cell types as well as artificial membranes.
Uses
Used in Biomedical Research:
DI-4-ANEPPS is used as a membrane potential dye for monitoring changes in membrane potential by fluorescence excitation changes. It is correlated to changes in the membrane potential of a cell, making it a valuable tool for studying cell physiology and function.
Used in Neuroscience:
In neuroscience, DI-4-ANEPPS is used as a fluorescent probe to measure the membrane potential of neurons. This helps researchers understand the electrical activity of neurons and their role in various neurological processes.
Used in Drug Screening:
DI-4-ANEPPS is used in drug screening applications to evaluate the effects of potential drugs on cell membrane potential. This can help identify compounds that modulate membrane potential and may have therapeutic applications in treating diseases related to membrane potential dysregulation.
Used in Metabolite Analysis:
DI-4-ANEPPS can also be used in metabolite analysis to study the effects of metabolic changes on cell membrane potential. This can provide insights into the relationship between metabolism and membrane potential, which may be relevant for understanding certain metabolic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 90134-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,1,3 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 90134-00:
(7*9)+(6*0)+(5*1)+(4*3)+(3*4)+(2*0)+(1*0)=92
92 % 10 = 2
So 90134-00-2 is a valid CAS Registry Number.
InChI:InChI=1/C28H36N2O3S/c1-3-5-17-30(18-6-4-2)28-13-12-26-22-25(10-11-27(26)23-28)9-8-24-14-19-29(20-15-24)16-7-21-34(31,32)33/h8-15,19-20,22-23H,3-7,16-18,21H2,1-2H3
90134-00-2Relevant articles and documents
Charge-Shift Probes of Membrane Potential. Synthesis
Hassner, A.,Birnbaum, D.,Loew, L. M.
, p. 2546 - 2551 (2007/10/02)
We are reporting two general synthetic approaches to a number of (aminostyryl)pyridinium dyes and their heterocyclic analogues which are of interest as electrochromic probes for membrane potential.The two routes which involve palladium-catalyzed coupling or aldol condensation permit considerable structure variations to be introduced in the dyes.Some spectral properties of the dyes are discussed.
