9014-67-9 Usage
Description
Aloxiprin, also known as 4-(4-chlorobenzoyl)-2-hydroxy-6-methylpyridine, is a nonsteroidal anti-inflammatory drug (NSAID) with both analgesic and antipyretic properties. It is a derivative of pyridine and exhibits its therapeutic effects by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins involved in inflammation, pain, and fever.
Source:
Aloxiprin is synthesized through a series of chemical reactions involving the chlorination of a benzoyl chloride derivative and subsequent condensation with a pyridine compound.
Production Methods:
The production of Aloxiprin involves the formation of the 4-chlorobenzoyl moiety, followed by its reaction with 2-hydroxy-6-methylpyridine to form the final compound.
Uses
Used in Pharmaceutical Industry:
Aloxiprin is used as an analgesic and antipyretic agent for the management of mild to moderate pain, fever, and inflammation. It is particularly effective in conditions such as headache, toothache, menstrual pain, and musculoskeletal disorders.
Used in Rheumatology:
In the field of rheumatology, Aloxiprin is used as an anti-inflammatory drug for the treatment of various rheumatic conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It helps in reducing inflammation, pain, and stiffness associated with these conditions.
Used in Gastroenterology:
Aloxiprin is also used in gastroenterology for the management of gastrointestinal disorders, such as peptic ulcers and inflammatory bowel disease. Its anti-inflammatory and analgesic properties help in alleviating pain and reducing inflammation in the gastrointestinal tract.
Brand Names:
Aloxiprin is available under various brand names, including Aloxipirine tablets, Lyman tabs, Palaprin forte, Paloxin, Palprin, Rumatral, Shin-rheufen, Superpyrin, and Tiatral. These formulations are used for the treatment of various pain and inflammatory conditions, as mentioned above.
World Health Organization (WHO)
Aloxiprin is a pro-drug of acetylsalicylic acid. See WHO comment
for acetylsalicylic acid.
Check Digit Verification of cas no
The CAS Registry Mumber 9014-67-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,1 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 9014-67:
(6*9)+(5*0)+(4*1)+(3*4)+(2*6)+(1*7)=89
89 % 10 = 9
So 9014-67-9 is a valid CAS Registry Number.
