90185-89-0Relevant articles and documents
PREPARATION AND CONFORMATIONAL STUDY OF CIS-5-METHYL-N1,N4-DIACETYL-2-PIPERAZINE-N'-METHYL-CARBOXAMIDE
Anteunis, Marc J. O.,Hosten, Noel G. C.,Borremans, Frans A. M.,Tavernier, Dirk K.
, p. 999 - 1010 (2007/10/02)
The preparation of the racemic title compound is reported.An extensive (1)H and (13)C nmr study reveals the presence of four rotameric states about the two amide bonds (Table 4) and discloses that all four isomers possess almost identical twist-boat ring shapes characterized by an endocyclic torsion angle along the C(α)-C(β) and C(δ)-C(ε) bond of -35+/-5 deg if an L-configuration is considered.