90220-25-0

Basic information

• Product Name: Benzenepropanesulfonamide
• CAS NO: 90220-25-0
• Molecular Formula: C9H13NO2S
• Molecular Weight: 199.274
• Mol File: 90220-25-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenepropanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanesulfonamide(90220-25-0)
• EPA Substance Registry System: Benzenepropanesulfonamide(90220-25-0)

Safety Data

• Hazardous Substances Data: 90220-25-0(Hazardous Substances Data)

Upstream product

• 80639-68-5 3-phenyl-1-propanesulphonyl azide 
• 77357-68-7 sodium 3-phenylpropane sulfinate 
• 637-59-2 1-Bromo-3-phenylpropane 
• 90220-58-9 sodium 3-phenylpropane-1-sulfonate 
• 63014-04-0 3-Phenyl-propane-1-sulfonyl chloride 
• 71-43-2 benzene 
• 110-82-7 cyclohexane 
• 89987-96-2 1,2-bis(3-phenylpropyl)disulfane 

Downstream Products

• 218601-34-4 N-[6-chloro-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-3-phenylpropanesulfonamide 
• 881652-47-7 3-phenyl-4,5-dihydro-isothiazole 1,1-dioxide 
• 405307-10-0 C₃₀H₂₈BrN₇O₆S 
• 405307-83-7 C₂₆H₂₇N₅O₆S 
• 863912-76-9 N-(3-phenylpropylsulfonyl)-α-dehydrovaline 
• 93808-41-4 3-(3-Phenyl-propylsulfonyl)-1-butyl-harnstoff 

Relevant articles and documents

Synthesis of Sulfones and Sulfonyl Derivatives using Sodium (tert-butyldimethylsilyl)oxymethanesulfinate

The present invention relates to a method for manufacturing a sulfone and sulfonyl derivative compound using sodium (tert-butyldimethylsilyl)oxymethanesulfinate, which is a novel organic sulfin salt, wherein the novel organic sulfin salt has good stability, environmental friendliness and economy, and is easy to handle, and thus significantly reduces the amount of transition metal catalysts and the amount of organic sulfin salts used when introducing aryl or alkenyl. Also, alkylation, arylation, amination, and fluorination are all possible during secondary functionalization. Therefore, the present invention can be usefully used in preparation and mass production of various kinds of sulfones and derivatives thereof including asymmetric sulfone derivatives.

A Versatile Reagent and Method for Direct Aliphatic Sulfonylation

An efficient methodology has been developed for the two-step synthesis of aliphatic sulfinate salts, sulfonamides, sulfonyl fluorides, and unsymmetrical sulfones on the basis of alkylation of a new versatile sulfonylating reagent. The new reagent is easily accessible in one step; the developed protocols are conducted under mild conditions and have a broad substrate scope. (Figure presented.).

Arylalkane-sulfonamides having endothelin-antagonist activity

The invention relates to novel aryl-alkane-sulfonamides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.