90260-13-2

Basic information

• Product Name: 3-FLUORO-4-METHYLBENZENESULFONYL CHLORIDE
• Synonyms: 3-FLUORO-4-METHYLBENZENESULFONYL CHLORIDE;3-FLUORO-4-METHYLBENZENESULPHONYL CHLORIDE;BUTTPARK 145\11-13;3-Fluoro-p-toluenesulphonyl chloride;Benzenesulfonyl chloride, 3-fluoro-4-methyl- (9CI);3-fluoro-p-toluenesulfonyl chloride;3-Fluoro-4-methylbenzenesulphonyl chloride 98%;3-Fluoro-4-methylbenzenesulphonylchloride98%
• CAS NO: 90260-13-2
• Molecular Formula: C₇H₆ClFO₂S
• Molecular Weight: 208.64
• Product Categories: Fluoro-contained benzenesulfonyl chloride series;SULFONYLHALIDE;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Fluorine series
• Mol File: 90260-13-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 46-50 °C(lit.)
• Boiling Point: 258.6 °C at 760 mmHg
• Flash Point: >110°C
• Appearance: White solid
• Density: 1.423 g/cm³
• Vapor Pressure: 0.022mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 3-FLUORO-4-METHYLBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-4-METHYLBENZENESULFONYL CHLORIDE(90260-13-2)
• EPA Substance Registry System: 3-FLUORO-4-METHYLBENZENESULFONYL CHLORIDE(90260-13-2)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 90260-13-2(Hazardous Substances Data)

Usage

Description

3-Fluoro-4-methylbenzenesulfonyl chloride is an organic chemical compound characterized by the presence of a fluorine atom at the 3-position and a methyl group at the 4-position on a benzene ring. It also features a sulfonyl chloride functional group attached to the benzene ring. 3-FLUORO-4-METHYLBENZENESULFONYL CHLORIDE is known for its potential applications in the synthesis of various organic compounds and pharmaceuticals.

Uses

Used in Pharmaceutical Industry:
3-Fluoro-4-methylbenzenesulfonyl chloride is used as a GCN2 modulator for the treatment, prevention, amelioration, control, or reduction of disorders related to GCN2. GCN2 (General Control Nonderepressible 2) is a protein kinase that plays a crucial role in the regulation of cellular stress responses and has been implicated in various diseases. By modulating the activity of GCN2, this compound can potentially offer therapeutic benefits in managing these disorders.

InChI:InChI=1/C7H6ClFO2S/c1-5-2-3-6(4-7(5)9)12(8,10)11/h2-4H,1H3

Relevant articles and documents

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