9028-53-9

Basic information

• Product Name: EC 1.1.1.47
• Synonyms: BETA-D-GLUCOSE: NADP+ 1-OXIDOREDUCTASE;GLUCOSE DEHYDROGENASE;GLUCOSE DEHYDROGENASE, NADP DEPENDENT;GDH;EC 1.1.1.47;EC 1.1.1.119;D-GLUCOSE DEHYDROGENASE BM;D-GLUCOSE DEHYDROGENASE BS
• CAS NO: 9028-53-9
• Molecular Formula: NULL
• Molecular Weight: 0
• EINECS: 232-836-9
• Product Categories: Oxidoreductases;Specialty Enzymes;1.1.x.x Acting on hydroxyl groups;1.x.x.x Oxidoreductases;Enzyme-Mediated Synthesis;OxidoreductasesEnzyme Class Index;Specialty Synthesis
• Mol File: 9028-53-9.mol
• Article Data: 0

Chemical Properties

• Appearance: white/powder
• Storage Temp.: 2-8°C
• CAS DataBase Reference: EC 1.1.1.47(CAS DataBase Reference)
• NIST Chemistry Reference: EC 1.1.1.47(9028-53-9)
• EPA Substance Registry System: EC 1.1.1.47(9028-53-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 9028-53-9(Hazardous Substances Data)

Usage

Description

EC 1.1.1.47, also known as Glycerol dehydrogenase, is an enzyme that catalyzes the oxidation of glycerol to dihydroxyacetone using NAD+ as a cofactor. It plays a crucial role in various metabolic pathways and has potential applications in diagnostics and biofuel cell research.
Source:
Glycerol dehydrogenase is found in various organisms, including bacteria, yeast, and plants.
Production Methods:
The enzyme can be produced through recombinant DNA technology or extracted from natural sources.

Uses

Used in Diagnostics:
EC 1.1.1.47 is used as a diagnostic tool for measuring glycerol levels in biological samples, which can be an indicator of various metabolic disorders and diseases.
Used in Biofuel Cell Research:
This product has been enhanced for energy efficiency and waste prevention when used in biofuel cell research. EC 1.1.1.47 is used as a catalyst in the oxidation of glycerol to generate electrical energy, contributing to the development of sustainable and eco-friendly energy sources.
Used in Cofactor Regeneration:
EC 1.1.1.47 is used for the regeneration of NAD(P)H in reductive processes, which is essential for maintaining the balance of coenzymes in metabolic reactions and improving the overall efficiency of enzymatic processes.

Biochem/physiol Actions

In bacteria, the membrane integrated glucose dehydrogenase catalyses the conversion of glucose to gluconic acid. It uses pyrroloquinoline quinone as a coenzyme. The intracellular glucose dehydrogenase lack this cofactor. It is a nicotinamide adenine dinucleotide (NADH) dependent enzyme.