9033-12-9
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Basic information
- Product Name: EC 4.4.1.5
- Synonyms: EC 4.4.1.5;GLYOXALASE I;S-LACTOYL-GLUTATHIONE METHYLGLYOXAL-LYASE [ISOMERIZING];glyoxalase I grade iv from yeast;glyoxalase I grade X from yeast;glyoxalase i from saccharomyces cerevisiae;glyoxylase I
- CAS NO:9033-12-9
- Molecular Formula:
- Molecular Weight: 0
- EINECS: 232-891-9
- Product Categories: N/A
- Mol File: 9033-12-9.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /buffered aqueous glycerol solution
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: EC 4.4.1.5(CAS DataBase Reference)
- NIST Chemistry Reference: EC 4.4.1.5(9033-12-9)
- EPA Substance Registry System: EC 4.4.1.5(9033-12-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9033-12-9(Hazardous Substances Data)
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9033-12-9 Usage
Description
EC 4.4.1.5, also known as Glyoxalase I, is an enzyme that catalyzes the conversion of methylglyoxal to S-lactoylglutathione using glutathione as a cofactor. It plays a crucial role in detoxifying methylglyoxal, a highly reactive dicarbonyl compound that can cause cellular damage.Used in Biochemical Assays:
EC 4.4.1.5 is used as a standard in Glyoxalase I assays for various organisms, such as C. dilatata females and brooded encapsulated embryos. It helps in assessing the enzyme activity and its role in detoxification processes.
Used in Calibration Curve Generation:
In the field of biochemistry and molecular biology, EC 4.4.1.5 is used as a standard for generating calibration curves. This allows for the accurate quantification of glyoxalase I levels in different tissues, such as brain tissues and cerebral microvessels, providing valuable insights into its biological functions and potential applications in various research and diagnostic settings.
Biochem/physiol Actions
Glyoxalase I is universally expressed and involved in the protection against cellular damage due to cytotoxic metabolites such as advanced glycation end products (AGEs). It is an integral component of the detoxification system, catalyzing the conversion of reactive, acyclic a-oxoaldehydes into the corresponding a-hydroxyacids in a glutathione-dependent manner.Check Digit Verification of cas no
The CAS Registry Mumber 9033-12-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,3 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.Calculate Digit Verification of CAS Registry Number 9033-12:
(6*9)+(5*0)+(4*3)+(3*3)+(2*1)+(1*2)=79
79 % 10 = 9
So 9033-12-9 is a valid CAS Registry Number.
9033-12-9Upstream product
9033-12-9Downstream Products
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EC 4.4.1.5
