90347-63-0

Basic information

• Product Name: 1-(2-iodo-4-methoxyphenyl)ethanone
• Synonyms: 1-(2-iodo-4-methoxyphenyl)ethanone
• CAS NO: 90347-63-0
• Molecular Weight: 276.074
• Mol File: 90347-63-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 68–70°C
• CAS DataBase Reference: 1-(2-iodo-4-methoxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-iodo-4-methoxyphenyl)ethanone(90347-63-0)
• EPA Substance Registry System: 1-(2-iodo-4-methoxyphenyl)ethanone(90347-63-0)

Safety Data

• Hazardous Substances Data: 90347-63-0(Hazardous Substances Data)

Usage

Preparation

Obtained by reaction of acetyl chloride with 3-iodoanisole in the presence of aluminium chloride in carbon disulfide.

Upstream product

• 766-85-8 3-methoxy-1-iodobenzene 
• 75-36-5 acetyl chloride 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 75-05-8 acetonitrile 
• 108-24-7 acetic anhydride 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 42465-53-2 1-(2-amino-4-methoxyphenyl)ethanone 
• 38487-85-3 4-methoxyanthranilonitrile 
• 105-53-3 diethyl malonate 

Downstream Products

• 89942-32-5 1-(4-hydroxy-2-iodo-phenyl)-ethanone 
• 108059-78-5 2-(2-Acetyl-5-methoxyphenylthio)benzoesaeure 
• 1192931-48-8 (E)-N-[1-(2-iodo-4-methoxyphenyl)ethylidene]-4-methoxyaniline 
• 153967-96-5 5-methoxy-2-vinylbenzoic acid 
• 1225288-95-8 3,5,6-tris(4-chlorophenyl)-1,2,4-tris(trifluoromethyl)benzene 
• 1326778-76-0 C₉H₁₀INO₂ 
• 1326778-73-7 (E)-1-(2-(4-chlorophenylamino)-4-methoxyphenyl)ethanone oxime 
• 1326778-72-6 (E)-1-(4-methoxy-2-(4-methoxyphenylamino)phenyl)ethanone oxime 
• 1326778-71-5 (E)-1-(4-methoxy-2-(phenylamino)phenyl)ethanone oxime 

Relevant articles and documents

Palladium-catalyzed: Ortho -halogen-induced deoxygenative approach of alkyl aryl ketones to 2-vinylbenzoic acids

The 2-vinylbenzoic acids have wide applications in the field of polymer chemistry and are key precursors for the synthesis of important bioactive molecules. Herein, an ortho-halogen-induced deoxygenative approach for the generation of 2-vinylbenzoic acids from alkyl aryl ketones by palladium catalysis is discovered and explored. This approach requires no base or stoichiometric additives and can be carried out through a simple one-step process. Furthermore, the present reaction is scalable up to one-gram scale. The commercially available palladium on carbon (5 wt%) was used as a heterogeneous catalyst and showed excellent recyclability (5 times) without significant loss in catalytic activity. Pleasingly, under our optimized conditions, the alpha alkyl substituted 2-iodoacetophenones exhibit good diastereoselectivity and predominantly (E)-2-vinylbenzoic acids were obtained with good to excellent yields.

Molybdenum(0)-promoted carbonylative cyclization of o-haloaryland β-haloalkenylimine derivatives by oxidative addition of a carbon(sp 2)-halogen bond: Preparation of two types of γ-lactams

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A 6-exo-trig radical cyclization approach to the hydrochrysene skeleton

The synthetic approach to a functionalized hydrochrysene skeleton is described. The route is highlighted by a Birch reduction-alkylation sequence and a 6-exo-trig radical cyclization.