90457-20-8

Basic information

• Product Name: Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 3',6'-bis(diethylamino)-2-(phenylamino)-
• CAS NO: 90457-20-8
• Molecular Formula: C34H36N4O2
• Molecular Weight: 532.685
• Mol File: 90457-20-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 3',6'-bis(diethylamino)-2-(phenylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 3',6'-bis(diethylamino)-2-(phenylamino)-(90457-20-8)
• EPA Substance Registry System: Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one, 3',6'-bis(diethylamino)-2-(phenylamino)-(90457-20-8)

Safety Data

• Hazardous Substances Data: 90457-20-8(Hazardous Substances Data)

Upstream product

• 81-88-9 rhodamine B 
• 100-63-0 phenylhydrazine 
• 1118784-85-2 rhodamine B 
• 69319-23-9 rhodamine B 

Downstream Products

• 1118784-85-2 rhodamine B 

Relevant articles and documents

Bioimaging of peroxynitrite in MCF-7 Cells by a new fluorescent probe rhodamine b phenyl hydrazide

Peroxynitrite is a potent oxidizing and nitrating agent which has detrimental effects on cells by altering the structure and function of biomolecules present within. A fluorescent probe rhodamine B phenyl hydrazide (RBPH) has been proposed for peroxynitrite (ONOO-) imaging in MCF-7 cells based on its oxidation property, which converts RBPH to pink colored and highly fluorescent rhodamine B. The fluorescence emission intensity of the rhodamine B produced in the above process is linearly related to the concentration of peroxynitrite. The method obeys Beer's law in the concentration range 2-20 nM and the detection limit has been found to be 1.4 nM. The possible reaction mechanism of peroxynitrite with RBPH to produce rhodamine B has been discussed with spectroscopic evidence. The Probe is selective to the peroxynitrite in the pH range 6-8 which is near physiological pH. Fluorescence microscopic studies suggest that the probe is cell permeable and hence peroxynitrite was imaged in MCF-7 cells.

Rhodamine-based derivatives for Cu2+ sensing: Spectroscopic studies, structure-recognition relationships and its test strips

A rhodamine spirolactam/2-hydrazinopyridine derivative was synthesized and characterized, which exhibited high selectivity to Cu2+ over other metal cations. The Cu2+ recognition of this rhodamine derivative could be detected by fluor