904962-56-7

Basic information

• Product Name: N-(5-Methyl-isoxazol-3-yl)-N-{1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-prop-2-ynyl}-4-nitro-benzenesulfonamide
• Synonyms: N-(5-Methyl-isoxazol-3-yl)-N-{1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-prop-2-ynyl}-4-nitro-benzenesulfonamide
• CAS NO: 904962-56-7
• Molecular Weight: 602.648
• Mol File: 904962-56-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(5-Methyl-isoxazol-3-yl)-N-{1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-prop-2-ynyl}-4-nitro-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-Methyl-isoxazol-3-yl)-N-{1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-prop-2-ynyl}-4-nitro-benzenesulfonamide(904962-56-7)
• EPA Substance Registry System: N-(5-Methyl-isoxazol-3-yl)-N-{1-methyl-3-[2-(4-phenoxy-phenoxy)-thiazol-5-yl]-prop-2-ynyl}-4-nitro-benzenesulfonamide(904962-56-7)

Safety Data

• Hazardous Substances Data: 904962-56-7(Hazardous Substances Data)

Upstream product

• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 831-82-3 4-Phenoxyphenol 
• 904962-37-4 5-[3-(tert-butyl-dimethyl-silanyloxy)-but-1-ynyl]-2-(4-phenoxy-phenoxy)-thiazole 
• 903886-77-1 5-iodo-2-(4-phenoxyphenoxy)thiazole 
• 903886-76-0 2-(4-phenoxyphenoxy)thiazole 
• 903886-90-8 4-[2-(4-phenoxyphenoxy)-1,3-thiazol-5-yl]but-3-yn-2-ol 
• 29699-89-6 N-(5-methyl-isoxazol-3-yl)-4-nitro-benzenesulfonamide 

Relevant articles and documents

The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: Polar region modifications

The structure-activity relationship study focused on the polar region of the HTS hit A-80040 (1) producing several series of potent and selective ACC2 inhibitors. The SAR suggests a compact lipophilic pocket that does not tolerate polar and ionic groups.