905580-80-5

Basic information

• Product Name: (2R,3R,4S,5R)-5-(6-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-9H-purin-9-yl)-4-fluoro-2-[(trityloxy)methyl]tetrahydrofuran-3-yl benzoate
• Synonyms: (2R,3R,4S,5R)-5-(6-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-9H-purin-9-yl)-4-fluoro-2-[(trityloxy)methyl]tetrahydrofuran-3-yl benzoate
• CAS NO: 905580-80-5
• Molecular Weight: 731.826
• Mol File: 905580-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S,5R)-5-(6-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-9H-purin-9-yl)-4-fluoro-2-[(trityloxy)methyl]tetrahydrofuran-3-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S,5R)-5-(6-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-9H-purin-9-yl)-4-fluoro-2-[(trityloxy)methyl]tetrahydrofuran-3-yl benzoate(905580-80-5)
• EPA Substance Registry System: (2R,3R,4S,5R)-5-(6-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-9H-purin-9-yl)-4-fluoro-2-[(trityloxy)methyl]tetrahydrofuran-3-yl benzoate(905580-80-5)

Safety Data

• Hazardous Substances Data: 905580-80-5(Hazardous Substances Data)

Upstream product

• 10277-74-4 (S)-1-Aminoindane 
• 234436-49-8 9-[3-O-benzoyl-2-deoxy-2-fluoro-5-O-(triphenylmethyl)-β-D-arabinofuranosyl]-6-chloro-9H-purine 

Downstream Products

• 905580-81-6 (2R,3R,4S,5R)-5-(6-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl benzoate 

Relevant articles and documents

INHIBITORS OF E1 ACTIVATING ENZYMES

This invention relates to compounds that inhibit El activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.