90559-99-2

Basic information

• Product Name: 1-(4-methylphenyl)-3-(N-nitroamidino)thiourea
• Synonyms: 1-(4-methylphenyl)-3-(N-nitroamidino)thiourea
• CAS NO: 90559-99-2
• Molecular Weight: 253.285
• Mol File: 90559-99-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(4-methylphenyl)-3-(N-nitroamidino)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methylphenyl)-3-(N-nitroamidino)thiourea(90559-99-2)
• EPA Substance Registry System: 1-(4-methylphenyl)-3-(N-nitroamidino)thiourea(90559-99-2)

Safety Data

• Hazardous Substances Data: 90559-99-2(Hazardous Substances Data)

Upstream product

• 556-88-7 nitroguanidine 
• 622-59-3 1-isothiocyanato-4-methylbenzene 

Downstream Products

• 1174909-56-8 [4-[4-amino-2-(4-methylphenylamino)thiazole-5-carbonyl]phenyl]-[4-amino-2-(4-methylphenylamino)thiazol-5-yl]methanone 
• 107401-68-3 (4-amino-2-p-tolylamino-thiazol-5-yl)-phenyl-methanone 
• 90349-95-4 N³-nitro-N⁵-p-tolyl-[1,2,4]thiadiazole-3,5-diamine 
• 107401-71-8 4-amino-5-(p-methylbenzoyl)-2-(p-methylphenylamino)thiazole 

Relevant articles and documents

Synthesis and cyclization of 1-(N-nitroamidino)thioureas to 2,4-diaminothiazoles

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One-pot sequential multicomponent route to 2,4-diaminothiazoles - A facile approach to bioactive agents for cancer therapeutics

A facile one-pot sequential three-component route to 2,4-diaminothiazoles is reported. The new approach employs the mildest reaction conditions and commercially available reagents to generate diverse 2-alkyl/arylamino-4-amino-5- aroyl/heteroylthiazoles in short reaction times, good yield, and purity.