905991-54-0

Basic information

• Product Name: methyl (4-{2-[(tert-butoxycarbonyl)(methyl)amino]ethoxy}-3-chlorophenyl)acetate
• Synonyms: methyl (4-{2-[(tert-butoxycarbonyl)(methyl)amino]ethoxy}-3-chlorophenyl)acetate
• CAS NO: 905991-54-0
• Molecular Weight: 357.834
• Mol File: 905991-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (4-{2-[(tert-butoxycarbonyl)(methyl)amino]ethoxy}-3-chlorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (4-{2-[(tert-butoxycarbonyl)(methyl)amino]ethoxy}-3-chlorophenyl)acetate(905991-54-0)
• EPA Substance Registry System: methyl (4-{2-[(tert-butoxycarbonyl)(methyl)amino]ethoxy}-3-chlorophenyl)acetate(905991-54-0)

Safety Data

• Hazardous Substances Data: 905991-54-0(Hazardous Substances Data)

Upstream product

• 33697-81-3 (3-chloro-4-hydroxy-phenyl)-acetic acid 
• 57017-95-5 methyl 3-chloro-4-hydroxyphenylacetate 
• 57561-39-4 methyl(2-hydroxyethyl)carbamic acid tert-butyl ester 

Downstream Products

• 905991-67-5 (3-chloro-4-{2-[(5-[1,2]dithiolan-3-yl-pentanoyl)-methyl-amino]-ethoxy}-phenyl)-acetic acid methyl ester 

Relevant articles and documents

Design and synthesis of the first generation of dithiolane thiazolidinedione- and phenylacetic acid-based PPARγ agonists

A series of novel derivatives of potent antioxidant vitamin, α-lipoic acid, and related analogues were designed, synthesized, and evaluated for their PPARγ agonist activities. Compounds 9a and the water soluble analogue 11e were found to be potent PPARγ agonists. Compound 9a appeared to have a significant role in improving insulin sensitivity and reducing triglyceride levels in fa/fa rats as well as inhibited proliferation of a variety of normal and neoplastic cultured human cell types. These novel compounds may prove efficacious not only in the treatment of Type 2 diabetes, but also atherosclerosis, prevention of vascular restenosis, and inflammatory skin diseases.