906093-30-9

Basic information

• Product Name: Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate)
• Synonyms: Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate);1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine acetate;1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine monoacetate
• CAS NO: 906093-30-9
• Molecular Formula: C₂H₄O₂*C₁₄H₁₈N₄
• Molecular Weight: 302.37148
• Mol File: 906093-30-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate)(906093-30-9)
• EPA Substance Registry System: Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate)(906093-30-9)

Safety Data

• Hazardous Substances Data: 906093-30-9(Hazardous Substances Data)

Usage

General Description

Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate) is a chemical compound with the molecular formula C16H20N4O2. It is a derivative of piperazine and is commonly used in the synthesis of pharmaceuticals and fine chemicals. Piperazine, 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)- (acetate) has potential applications in the treatment of various medical conditions due to its pharmacological properties. The acetate group in the molecule makes it more soluble in organic solvents and enhances its stability. Overall, this chemical has promising potential for pharmaceutical research and development.

Upstream product

• 64-19-7 acetic acid 
• 100-63-0 phenylhydrazine 
• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 
• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 
• 401566-79-8 1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine 

Downstream Products

• 401566-80-1 tert-butyl (2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]-2-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidine-1-carboxylate 
• 760937-92-6 3-{(2S,4S)-1-(1,1-dimethylethyloxycarbonyl)-4-[4-(3-methyl-1-phenyl-1H-pyrazole-5-yl)piperazin-1-yl]pyrrolidine-2-ylcarbonyl}thiazolidine 

Relevant articles and documents

For the preparation of pyrazole derivatives

The present invention provides a prolinamide compound useful as a drug or the like and an industrially advantageous method for producing a piperazinyl pyrazole compound that is a production intermediate of the prolinamide compound. Specifically, the invention is a method for producing a compound represented by general formula (1) as represented by the following formula (where the symbols in the formula are the same as defined in the specification) or a salt thereof, wherein a compound represented by general formula (2) is produced, a pyrazole ring being formed via a reaction between a compound represented by general formula (3) and phosphorus pentasulfide; and, once the compound represented by general formula (2) is deprotected, a carboxylate of a compound represented by general formula (6) is produced, the compound obtained by forming a carboxylic acid and a salt.

PROCESS FOR THE PREPARATION OF 1-(3-METHYL-1-PHENYL-1H-PYRAZOL-5-YL)PIPERAZINE

The present invention provides a process for the preparation of 1-(3-methyl-1- phenyl-1H-pyrazol-5-yl)piperazine of Formula (III), or salts thereof. The invention also provides a process for the preparation of {(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5- yl)piperazin-1-yl]pyrrolidin-2-yl}(1,3-thiazolidin-3-yl)methanone, or salts thereof, using 1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazine of Formula (III), or salts thereof.