906371-79-7

Basic information

• Product Name: (2-chloropyridin-3-yl)-(4-methoxybenzyl)amine
• Synonyms: (2-chloropyridin-3-yl)-(4-methoxybenzyl)amine
• CAS NO: 906371-79-7
• Molecular Formula: C₁₃H₁₃ClN₂O
• Molecular Weight: 249
• Mol File: 906371-79-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-chloropyridin-3-yl)-(4-methoxybenzyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloropyridin-3-yl)-(4-methoxybenzyl)amine(906371-79-7)
• EPA Substance Registry System: (2-chloropyridin-3-yl)-(4-methoxybenzyl)amine(906371-79-7)

Safety Data

• Hazardous Substances Data: 906371-79-7(Hazardous Substances Data)

Upstream product

• 6298-19-7 2-chloro-3-aminopyridine 
• 123-11-5 4-methoxy-benzaldehyde 
• 386275-34-9 C₁₃H₁₁ClN₂O 

Downstream Products

• 906532-78-3 1-(2-chloro-pyridin-3-yl)-1-(4-methoxy-benzyl)urea 
• 1365094-37-6 2-iodo-1-(4-methoxybenzyl)-1H-imidazo[4,5-b]pyridine 
• 1365094-38-7 4-(1-(4-methoxybenzyl)-1H-imidazo[4,5-b]pyridin-2-yl)morpholine 
• 1365094-39-8 N-butyl-1-(4-methoxybenzyl)-1H-imidazo[4,5-b]pyridin-2-amine 
• 1365094-32-1 1-(4-methoxybenzyl)-2-methyl-1H-imidazo[4,5-b]pyridine 
• 1365094-28-5 1-(4-methoxybenzyl)-1H-imidazo[4,5-b]pyridine 
• 185669-66-3 N-(4-methoxybenzyl)pyridine-3-amine 

Relevant articles and documents

Synthesis of imidazo[4,5-b]pyridines and imidazo[4,5-b]pyrazines by palladium catalyzed amidation of 2-chloro-3-amino-heterocycles

A facile synthesis of imidazo[4,5-b]pyridines and-pyrazines is described using a Pd-catalyzed amide coupling reaction. This reaction provides quick access to products with substitution at N1 and C2. A model system relevant to the natural product pentosidi

Efficient access to cyclic ureas via Pd-catalyzed cyclization

An efficient regioselective method for the preparation of structurally diverse imidazopyridinones and benzoimidazolones starting from readily available and economical starting materials is described. High-yielding reductive alkylation of electron-deficient o-haloarylamines followed by treatment with inexpensive N-chlorosulfonyl isocyanate afforded primary ureas in good overall yields. A Pd-catalyzed urea cyclization reaction furnished imidazopyridinones and benzoimidazolones in excellent yields. Overall, the developed chemistry provides rapid access to pharmaceutically important heterocyclic compounds with high efficiency.