90656-51-2

Basic information

• Product Name: Butanamide, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-, (E)-
• CAS NO: 90656-51-2
• Molecular Formula: C17H16ClFN2O2
• Molecular Weight: 334.778
• Mol File: 90656-51-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanamide, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-, (E)-(90656-51-2)
• EPA Substance Registry System: Butanamide, 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]-, (E)-(90656-51-2)

Safety Data

• Hazardous Substances Data: 90656-51-2(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 29558-88-1 4-chlorobenzoic acid 4-fluorophenyl ester 
• 371-41-5 4-Fluorophenol 
• 62433-26-5 (4-chlorophenyl)-(5-fluoro-2-hydroxyphenyl)methanone 
• 13031-62-4 4-aminobutyric acid amide hydrochloride 

Relevant articles and documents

New anticonvulsants: Schiff bases of γ-aminobutyric acid and γ-aminobutyramide

Schiff bases of γ-aminobutyric acid (γAbu) and γ-aminobutyramide (γAbuNH2) were prepared and tested for anticonvulsant and γAbu mimetic activity. 4-[[(4-Chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]butanoic acid monosodium salt (4) and 4-[[(4-chlorophenyl)(5-fluoro-2-hydroxyphenyl)methylene]amino]butanamide (5) blocked bicuculline-induced lethality and convulsions and displaced [3H]γAbu from its membrane binding sites. In the rat dorsal root sensory ganglion, compound 4 exhibited γAbu agonist properties. Compounds 4 and 5 are thus anticonvulsants and directly acting γAbu mimetics.