90670-14-7

Basic information

• Product Name: Pentanoic acid, 4-hydroxy-2-(phenylthio)-, methyl ester
• CAS NO: 90670-14-7
• Molecular Formula: C12H16O3S
• Molecular Weight: 240.323
• Mol File: 90670-14-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pentanoic acid, 4-hydroxy-2-(phenylthio)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoic acid, 4-hydroxy-2-(phenylthio)-, methyl ester(90670-14-7)
• EPA Substance Registry System: Pentanoic acid, 4-hydroxy-2-(phenylthio)-, methyl ester(90670-14-7)

Safety Data

• Hazardous Substances Data: 90670-14-7(Hazardous Substances Data)

Upstream product

• 84796-81-6 4-Oxo-2-phenylsulfanyl-pentanoic acid 
• 103-04-8 (phenylthio)acetic acid 
• 84796-82-7 methyl 4-oxo-2-(phenylthio)pentanoate 

Downstream Products

• 53138-46-8 (+/-)-cis,trans-4-methyl-2-phenylsulfanylbutyrolactone 
• 591-11-7 5-methyl-5H-furan-2-one 
• 53138-50-4 (+/-)-cis,trans-4-methyl-2-phenylsulfinylbutyrolactone 

Relevant articles and documents

Michael Reaction of Conjugated Nitro Olefins with Carboxylic Acid Dianions and with Ester Enolates: New Synthesis of γ-Keto Acids and γ-Keto Esters

Base-sensitive conjugated nitro olefins 2 reacted with lithium dianions of carboxylic acids 3 or with lithium enolates of esters 4 at a low temperature of ca. -100 deg C, and subsequent treatment of the Michael adducts with aqueous acid yielded γ-keto acids 5 or esters 5' in a one-pot operation, respectively.Results of both the reactions have been compared.Some applications of the resulting γ-keto esters in organic synthesis have also been demonstrated in lactone synthesis and cyclenone annulation.