90763-46-5Relevant articles and documents
Synthesis, characterisation and metal complexation reactions of two calix[4]arene derivatives functionalised with pendant benzamide arms
McGinley, John,McKee, Vickie,Walsh, John M.D.
, p. 57 - 62 (2011)
Two calix[4]arene derivatives (3 and 4) functionalised at the lower rim with pendant benzamide arms were successfully synthesised and characterised, with the X-ray crystal structure of 3 being determined. Only 4 took part in some metal ion complexation re
Synthesis and evaluation of in vitro antiplatelet aggregation activities of 2-Methoxy-5-Aminobenzamides
Liu, Lili,Liu, Xiujie,Chen, Guangling,Qiu, Kai
, p. 1040 - 1050 (2019/10/28)
Objective: According to the principles of drug design, the structures of picotamide and betrixaban were combined to design novel series of 2-methoxy-5-aminobenzamides. A total of twenty new compounds 1a-1t have been synthesized and evaluated for their ant
A model β-sheet interaction and thermodynamic analysis of β-strand mimetics
Robinson, Colin W.,Rye, Carl S.,Chessum, Nicola E. A.,Jones, Keith
supporting information, p. 7402 - 7407 (2015/11/27)
β-Sheet mediated protein-protein interactions are involved in key signalling pathways in diseases such as cancer. We present small molecule β-strand mimetics and investigate their interactions with a model tripeptide. Using 1H NMR, the thermodynamic parameters for their binding are determined. These give insight into this biologically important interaction.