90778-41-9Relevant articles and documents
ADDITION CONJUGUEE DES α,ω-bis(BROMOMAGNESIO)ALCANES SUR LES COUMARINES
Cannone, P.,Caron, H.,Foscolos, G.
, p. 865 - 872 (2007/10/02)
Reactions of 1,4-bis(bromomagnesio)butane and 1,5-bis(bromomagnesio)pentane with coumarin and 6-methylcoumarin gave a mixture of 1-(o-hydroxystyryl)cycloalkanol and 4-alkyl-3,4-dihydrocoumarin.A large difference in product distribution was observed between the two bifunctional reagents.Annelation was favored by the use of 1,4-bis(bromomagnesio)butane, whereas conjugate addition was observed with 1,5-bis(bromomagnesio)pentane and even in the use of 4-methylcoumarin.