90793-64-9 Usage
Description
Ethyl 2-(2,6-dichlorophenyl)acetate is an organic compound that features a 2,6-dichlorophenyl group attached to an ethyl acetate moiety. This chemical entity is characterized by its potential reactivity and structural features that make it a valuable intermediate in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
Ethyl 2-(2,6-dichlorophenyl)acetate is utilized as a key intermediate in the synthesis of heteroarylaminonaphthyridinone derivatives. These derivatives are of significant interest due to their application as multiple kinase pathway inhibitors, which are crucial in the development of targeted therapies for various diseases, including cancer and other proliferative disorders.
The use of ethyl 2-(2,6-dichlorophenyl)acetate in this context highlights its importance in medicinal chemistry, where it contributes to the creation of novel and effective treatments by modulating the activity of specific kinase pathways. This application underscores the compound's role in advancing the field of drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 90793-64-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,7,9 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 90793-64:
(7*9)+(6*0)+(5*7)+(4*9)+(3*3)+(2*6)+(1*4)=159
159 % 10 = 9
So 90793-64-9 is a valid CAS Registry Number.
90793-64-9Relevant articles and documents
MULTIPLE KINASE PATHWAY INHIBITORS
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Page/Page column 267-269; 274, (2014/04/17)
Kinase with inhibitory activity against kinases disposed in multiple signaling pathways and their therapeutic uses.
Palladium-catalyzed oxidative carbonylation of benzylic C-H bonds via nondirected C(sp3)-H activation
Xie, Pan,Xie, Yinjun,Qian, Bo,Zhou, Han,Xia, Chungu,Huang, Hanmin
supporting information; experimental part, p. 9902 - 9905 (2012/08/08)
A new strategy for generating benzylpalladium reactive species from toluenes via nondirected C(sp3)-H activation has been developed. This led to construction of an efficient Pd-catalyzed reaction protocol for the oxidative carboxylation of benzylic C-H bonds to form substituted 2-phenylacetic acid esters and derivatives from inexpensive, commercially available starting materials.
Enantioselective Protonation of Samarium Enolates by a C2-Symmetric Chiral Diol
Takeuchi, Seiji,Ohira, Akiko,Miyoshi, Norikazu,Mashio, Hajime,Ohgo, Yoshiaki
, p. 1763 - 1780 (2007/10/02)
High enantioselectivity (up to 97percentee) have been achieved in the protonation of samarium enolates which were generated by SmI2-mediated cross-coupling reaction between unsymmetrical dialkylketene and allyl iodide, using, using a C2-symmetr
