90816-92-5Relevant articles and documents
Synthesis of N,N′,N″-trisubstituted thiourea derivatives and their antagonist effect on the vanilloid receptor
Park, Hyeung-Geun,Park, Mi-Kyung,Choi, Ji-Yeon,Choi, Sea-Hoon,Lee, Jihye,Park, Boon-Saeng,Kim, Myoung Goo,Suh, Young-Ger,Cho, Hawon,Oh, Uhtaek,Lee, Jeewoo,Kim, Hee-Doo,Park, Young-Ho,Koh, Hyun-Ju,Lim, Kyung Min,Moh, Joo-Hyun,Jew, Sang-Sup
, p. 601 - 604 (2007/10/03)
Twenty-seven N,N′,N″-trisubstituted thiourea derivatives were prepared. Among them, 1-[3-(4′-hydroxy-3′-methoxy-phenyl)-propyl]-1,3-diphenethyl- thiourea (8l, IC50=0.32 μM), showed 2-fold higher antagonistic activity than that of capsazepine (3