908239-56-5Relevant articles and documents
'Reverse' α-ketoamide-based p38 MAP kinase inhibitors
Montalban, Antonio Garrido,Boman, Erik,Chang, Chau-Dung,Ceide, Susana Conde,Dahl, Russell,Dalesandro, David,Delaet, Nancy G.J.,Erb, Eric,Gibbs, Andrew,Kahl, Jeff,Kessler, Linda,Lundstroem, Jan,Miller, Stephen,Nakanishi, Hiroshi,Roberts, Ed,Saiah, Eddine,Sullivan, Robert,Wang, Zhijun,Larson, Christopher J.
, p. 5456 - 5459 (2008)
We have identified a second series of potent p38 inhibitors. As with our first generation series, these compounds are based on an α-ketoamide scaffold. The reversal of the ketoamide order, however, introduces more chemical flexibility and in addition resu
