908256-15-5

Basic information

• Product Name: 7-((R)-2,3-hydroxypropylamino)-3-(2-trifluoromethoxyphenyl)-2H-isoquinolin-1-one
• Synonyms: 7-((R)-2,3-hydroxypropylamino)-3-(2-trifluoromethoxyphenyl)-2H-isoquinolin-1-one
• CAS NO: 908256-15-5
• Molecular Weight: 394.35
• Mol File: 908256-15-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-((R)-2,3-hydroxypropylamino)-3-(2-trifluoromethoxyphenyl)-2H-isoquinolin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-((R)-2,3-hydroxypropylamino)-3-(2-trifluoromethoxyphenyl)-2H-isoquinolin-1-one(908256-15-5)
• EPA Substance Registry System: 7-((R)-2,3-hydroxypropylamino)-3-(2-trifluoromethoxyphenyl)-2H-isoquinolin-1-one(908256-15-5)

Safety Data

• Hazardous Substances Data: 908256-15-5(Hazardous Substances Data)

Upstream product

• 66211-46-9 (R)-3-amino-1,2-propanediol 

Relevant articles and documents

1-(2H)-ISOQUINOLONE DERIVATIVE

The present invention provides a compound having high antitumor activity, which is useful for therapeutic and preventive agents effective for proliferative diseases such as cancer; a production method thereof; an intermediate compound useful for such production; and a pharmaceutical composition comprising such a compound. The present invention provides a compound represented by the formula (1): wherein X represents an aryl group or heteroaryl group which may be substituted, Cy represents a 4- to 7-membered monocyclic heterocyclic ring or a 8- to 10-membered condensed heterocyclic ring which may be substituted, and Z represents O, S, or NRa; or a prodrug thereof; or a pharmaceutically acceptable salt thereof; and a pharmaceutical and a pharmaceutical composition which comprise the compound.